Restasis and Ocaliva drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Restasis (cyclosporine) and Ocaliva (obeticholic acid). Common drug interactions include pruritus among females.
The phase IV clinical study analyzes what interactions people have when they take Restasis and Ocaliva. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.
What is Restasis?
Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.
What is Ocaliva?
Ocaliva has active ingredients of obeticholic acid. eHealthMe is studying from 6,919 Ocaliva users. Check the latest studies of Ocaliva.
30 people who take Restasis and Ocaliva together, and have interactions are studied.
What are the common drug interactions of Restasis and Ocaliva, by gender? *:
female:
- Pruritus (severe itching of the skin)
- Diarrhoea
- Insomnia (sleeplessness)
- Nausea (feeling of having an urge to vomit)
- Neoplasm malignant (cancer tumour)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Depression
- Dry mouth
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Stress
male:
n/a
What are the common drug interactions of Restasis and Ocaliva, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Abdominal pain
50-59:
- Dysgeusia (disorder of the sense of taste)
- Confusional state
- Constipation
60+:
- Pruritus (severe itching of the skin)
- Constipation
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Breast cancer
- Hypersensitivity
- Dizziness
- Insomnia (sleeplessness)
What are the existing conditions these people have? *
- Biliary Cirrhosis Primary (primary biliary cirrhosis (pbc) is a long-term liver disease that damages the small bile ducts in the liver. the build-up of bile damages the liver): 6 people, 20.00%
- Fungal Infection: 2 people, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Restasis and Ocaliva?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Restasis and Ocaliva:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ocaliva:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restasis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ocaliva and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on cyclosporine and obeticholic acid (the active ingredients of Restasis and Ocaliva, respectively), and Restasis and Ocaliva (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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