Retin-a and Dexamethasone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Retin-a (tretinoin) and Dexamethasone (dexamethasone). Common drug interactions include anhedonia among females and intestinal perforation among males.

The phase IV clinical study analyzes what interactions people have when they take Retin-a and Dexamethasone. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Retin-a?

Retin-a has active ingredients of tretinoin. It is often used in acne. eHealthMe is studying from 2,475 Retin-a users. Check the latest studies of Retin-a.

What is Dexamethasone?

Dexamethasone has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 161,927 Dexamethasone users. Check the latest studies of Dexamethasone.

On Jul, 17, 2026

24 people who take Retin-a and Dexamethasone together, and have interactions are studied.

Retin-a and Dexamethasone drug interactions.

What are the common drug interactions of Retin-A and Dexamethasone, by gender? *:

female:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Device related infection
Gait disturbance
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Injury
Insomnia (sleeplessness)
Neck pain
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain

male:

Intestinal perforation (complete penetration of the wall of the intestine)
Anaemia (lack of blood)
Mitral valve incompetence (inefficient heart valve)
Neonatal disorder (disease of neonates)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)
Osteosclerosis (an elevation in bone density)
Pain
Pain in extremity
Alopecia (absence of hair from areas of the body)

What are the common drug interactions of Retin-A and Dexamethasone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Irritability

30-39:

n/a

40-49:

Bradycardia (abnormally slow heart action)

50-59:

Anxiety
Arthralgia (joint pain)
Device related infection
Gait disturbance
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Injury
Insomnia (sleeplessness)
Neck pain
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain

60+:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pain in extremity
Constipation
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Hyperhidrosis (abnormally increased sweating)
Hypoaesthesia (reduced sense of touch or sensation)
Mitral valve incompetence (inefficient heart valve)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Osteonecrosis of jaw (death of bone of jaw)

What are the existing conditions these people have? *

Rashes (redness): 3 people, 12.50%
Neuropathy Peripheral (surface nerve damage): 3 people, 12.50%
Nausea And Vomiting: 3 people, 12.50%
Nausea (feeling of having an urge to vomit): 3 people, 12.50%
Hypersensitivity: 3 people, 12.50%
Endometrial Cancer: 3 people, 12.50%
Depression: 3 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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