Riboflavin and Abilify drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Riboflavin (riboflavin (vitamin b2)) and Abilify (aripiprazole). Common drug interactions include glycosylated haemoglobin increased among females and cardiomyopathy among males.

The phase IV clinical study analyzes what interactions people have when they take Riboflavin and Abilify. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Riboflavin?

Riboflavin has active ingredients of riboflavin (vitamin b2). It is often used in migraine. eHealthMe is studying from 2,869 Riboflavin users. Check the latest studies of Riboflavin.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,455 Abilify users. Check the latest studies of Abilify.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 21, 2026

41 people who take Riboflavin and Abilify together, and have interactions are studied.

Riboflavin and Abilify drug interactions.

What are the common drug interactions of Riboflavin and Abilify, by gender? *:

female:

  1. Glycosylated haemoglobin increased
  2. Haematocrit
  3. Hypervolaemia (abnormally increased volume of blood)
  4. Impaired work ability
  5. Infusion site discolouration
  6. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  7. Knee arthroplasty
  8. Loss of employment
  9. Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
  10. Oxygen saturation decreased

male:

  1. Cardiomyopathy (weakening of the heart muscle)
  2. Hepatic congestion (liver congestion)
  3. Dermatillomania (skin picking disorders)
  4. Dysphagia (a condition in which swallowing is difficult or painful)
  5. Eating disorder
  6. Emotional distress
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Hiatus hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm)
  9. Injury
  10. Lymphocyte count increased

What are the common drug interactions of Riboflavin and Abilify, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Aggression
  2. Anger
  3. Diarrhoea
  4. Nausea (feeling of having an urge to vomit)
  5. Retching (strong involuntary effort to vomit)
  6. Vomiting

20-29:

  1. Dizziness
  2. Electrolyte imbalance
  3. Haematocrit
  4. Hypervolaemia (abnormally increased volume of blood)
  5. Impaired work ability
  6. Infusion site discolouration
  7. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  8. Loss of employment
  9. Oxygen saturation decreased
  10. Panic attack

30-39:

  1. Cardiomyopathy (weakening of the heart muscle)
  2. Hepatic congestion (liver congestion)
  3. Hepatic steatosis (fatty liver disease)
  4. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Head injury
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Arthralgia (joint pain)
  9. Bankruptcy
  10. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)

40-49:

  1. Anxiety
  2. Arthralgia (joint pain)
  3. Joint swelling
  4. Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
  5. Suicidal ideation

50-59:

  1. Staphylococcal infection (an infection with staphylococcus bacteria)
  2. Headache (pain in head)
  3. Influenza
  4. Infusion related reaction
  5. Nausea (feeling of having an urge to vomit)
  6. Alanine aminotransferase increased
  7. Dyspnoea (difficult or laboured respiration)
  8. Knee arthroplasty
  9. Pneumonia
  10. Productive cough

60+:

  1. Diarrhoea
  2. Dizziness
  3. Neuropathy peripheral (surface nerve damage)
  4. Peripheral swelling

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 14 people, 34.15%
  2. Pain: 6 people, 14.63%
  3. Post Laminectomy Syndrome: 5 people, 12.20%
  4. Neuralgia (pain in one or more nerves): 5 people, 12.20%
  5. Neck Pain: 5 people, 12.20%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 12.20%
  7. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back)): 5 people, 12.20%
  8. High Blood Pressure: 5 people, 12.20%

* Approximation only. Some reports may have incomplete information.

Do you take Riboflavin and Abilify?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Riboflavin and Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Riboflavin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Riboflavin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on riboflavin (vitamin b2) and aripiprazole (the active ingredients of Riboflavin and Abilify, respectively), and Riboflavin and Abilify (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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