Rivaroxaban and Zetia drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rivaroxaban (rivaroxaban) and Zetia (ezetimibe). Common drug interactions include anaemia among females and liver abscess among males.
The phase IV clinical study analyzes what interactions people have when they take Rivaroxaban and Zetia. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Rivaroxaban?
Rivaroxaban has active ingredients of rivaroxaban. It is often used in blood clots. eHealthMe is studying from 26,543 Rivaroxaban users. Check the latest studies of Rivaroxaban.
What is Zetia?
Zetia has active ingredients of ezetimibe. It is often used in high blood cholesterol. eHealthMe is studying from 49,113 Zetia users. Check the latest studies of Zetia.
24 people who take Rivaroxaban and Zetia together, and have interactions are studied.

What are the common drug interactions of Rivaroxaban and Zetia, by gender? *:
female:
- Anaemia (lack of blood)
- Rectal cancer (cancer of rectum)
- Embolic stroke (stroke due to obstruction due to an embolus)
- Melaena (the passage of black, tarry stools)
- Chronic kidney disease
- Alopecia (absence of hair from areas of the body)
- Blood urine present
- Drug ineffective
- Haemorrhagic transformation stroke (haemorrhages develop inside areas of ischemia)
- Pruritus (severe itching of the skin)
male:
- Liver abscess (pus in liver)
- Pyrexia (fever)
- Memory impairment
- Speech disorder
- Chest discomfort
- Chronic kidney disease
- Dyspnoea exertional (breathlessness or shortness of breath)
- Gait disturbance
- Hyperhidrosis (abnormally increased sweating)
- Intermittent claudication
What are the common drug interactions of Rivaroxaban and Zetia, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Haemorrhagic transformation stroke (haemorrhages develop inside areas of ischemia)
- Altered state of consciousness (altered state of mind)
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Headache (pain in head)
- Hydrocephalus (water on the brain)
- Intraventricular haemorrhage (intraventricular bleeding)
- Memory impairment
- Speech disorder
60+:
- Liver abscess (pus in liver)
- Pyrexia (fever)
- Blood urine present
- Drug ineffective
- Hepatocellular carcinoma (liver cancer)
- Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
- Pruritus (severe itching of the skin)
- Renal injury (kidney injury)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Abdominal pain
What are the existing conditions these people have? *
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 25.00%
- Dyslipidaemia (abnormal amount of lipids): 5 people, 20.83%
- Peripheral Arterial Occlusive Disease (reproducible ischemic muscle pain): 4 people, 16.67%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 16.67%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 4 people, 16.67%
- Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 3 people, 12.50%
- Prinzmetal Angina (cardiac chest pain at rest that occurs in cycles): 3 people, 12.50%
- High Blood Pressure: 3 people, 12.50%
- Fever: 3 people, 12.50%
- Depression: 3 people, 12.50%
* Approximation only. Some reports may have incomplete information.
Do you take Rivaroxaban and Zetia?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Rivaroxaban (26,543 reports)
- Zetia (49,113 reports)
Browse all drug interactions of Rivaroxaban and Zetia:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rivaroxaban:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zetia:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rivaroxaban and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zetia and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on rivaroxaban and ezetimibe (the active ingredients of Rivaroxaban and Zetia, respectively), and Rivaroxaban and Zetia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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