Rocephin and Celestone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rocephin (ceftriaxone sodium) and Celestone (betamethasone). Common drug interactions include hepatic cirrhosis among females and angioneurotic oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Rocephin and Celestone. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Celestone?

Celestone has active ingredients of betamethasone. It is often used in bursitis. eHealthMe is studying from 1,788 Celestone users. Check the latest studies of Celestone.

On Jul, 16, 2026

42 people who take Rocephin and Celestone together, and have interactions are studied.

Rocephin and Celestone drug interactions.

What are the common drug interactions of Rocephin and Celestone, by gender? *:

female:

Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic failure (liver failure)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypotension (abnormally low blood pressure)
Intervertebral disc compression (spinal disc compression)
Intervertebral disc protrusion (spinal disc protrusion)

male:

Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Bradycardia (abnormally slow heart action)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic kidney disease
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)
Craniosynostosis (a baby is born with an abnormally shaped skull or develops one during growth)
Drug exposure during pregnancy
Gastric dysplasia (stomach with abnormality of development)
Hypertensive nephropathy (hypertensive renal disease)

What are the common drug interactions of Rocephin and Celestone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anger
Drug dependence
Sedation
Anxiety
Concussion (short loss of normal brain function in response to a head injury)
Exacerbation of anxiety (increase in the severity of anxiety)
Face oedema (swelling of face)
Herpes simplex (herpes simplex is a common viral infection)
Major depressive disorder (a condition characterized by a long-lasting depressed mood or marked loss of interest or pleasure)

40-49:

Dermatitis acneiform (dermatoses including acne vulgaris, rosacea, folliculitis, and perioral dermatitis)
Drug ineffective
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Headache (pain in head)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hepatic failure (liver failure)
Hyperkalaemia (damage to or disease of the kidney)
Hypokalaemia (low potassium)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Joint effusion (presence of extra fluid in joint covering)

50-59:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Chronic kidney disease

60+:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Shock (a life-threatening condition with symptoms like low blood pressure, weakness, shallow breathing, cold, clammy skin)
Abscess (pus)
Actinomycosis (infection that causes sores, or abscesses)
Acute respiratory distress syndrome
Acute respiratory failure
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Aortic arteriosclerosis (hardening of the aortic arteries)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 9.52%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 7.14%
Pneumonia: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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