Rocephin and Itraconazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rocephin (ceftriaxone sodium) and Itraconazole (itraconazole). Common drug interactions include haematoma among females and interstitial lung disease among males.

The phase IV clinical study analyzes what interactions people have when they take Rocephin and Itraconazole. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Itraconazole?

Itraconazole has active ingredients of itraconazole. It is often used in fungal infection. eHealthMe is studying from 12,372 Itraconazole users. Check the latest studies of Itraconazole.

On Jul, 26, 2026

24 people who take Rocephin and Itraconazole together, and have interactions are studied.

Rocephin and Itraconazole drug interactions.

What are the common drug interactions of Rocephin and Itraconazole, by gender? *:

female:

Haematoma (collection of blood outside the blood vessels)
Atelectasis (partial or complete collapse of the lung)
Coma (state of unconsciousness lasting more than six hours)
Diarrhoea
Disease recurrence
Febrile neutropenia (fever with reduced white blood cells)
Haemorrhage (bleeding)
Abdominal abscess (collection of pus in abdomen)
Ageusia (loss of taste functions of the tongue)
Asthenia (weakness)

male:

Interstitial lung disease
Inappropriate antidiuretic hormone secretion
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Hair colour changes
Hypertension (high blood pressure)
Hyperthermia (body temperature greatly above normal)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Liposarcoma (a cancer tumour that arises in fat cells in deep soft tissue)

What are the common drug interactions of Rocephin and Itraconazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Human herpesvirus 6 infection

30-39:

Atelectasis (partial or complete collapse of the lung)
Disease recurrence
Febrile neutropenia (fever with reduced white blood cells)
Blood culture positive
Platelet count decreased
Staphylococcal bacteraemia (a bacterial infection of blood)
Staphylococcal infection (an infection with staphylococcus bacteria)
White blood cell count decreased

40-49:

Dysgeusia (disorder of the sense of taste)
Hair colour changes
Hypertension (high blood pressure)
Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Liposarcoma (a cancer tumour that arises in fat cells in deep soft tissue)
Malaise (a feeling of general discomfort or uneasiness)
Malignant pleural effusion (a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue lining of lung)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)

50-59:

Activated partial thromboplastin time prolonged
Blood lactate dehydrogenase increased
Cardiac failure congestive
Haemoglobin decreased
Interstitial lung disease
Malignant neoplasm progression (cancer tumour came back)
Performance status decreased
Red blood cell count decreased

60+:

Interstitial lung disease
Pneumonia bacterial (pneumonia associated with bacterial infection)
Dizziness
Enteritis infectious (infection with feline parvovirus (fpv), also known as feline panleucopenia virus)
Haemorrhage (bleeding)
Hyperthermia (body temperature greatly above normal)
Neoplasm malignant (cancer tumour)
Neoplasm progression (growth of tumour)
Serum ferritin increased
Cardiac failure

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 20.83%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 4 people, 16.67%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 12.50%
Pneumonia Bacterial (pneumonia associated with bacterial infection): 2 people, 8.33%
Neuralgia (pain in one or more nerves): 2 people, 8.33%
Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 2 people, 8.33%
Liposarcoma (a cancer tumour that arises in fat cells in deep soft tissue): 2 people, 8.33%
Cachexia (loss of weight): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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