Rowasa and Flonase drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rowasa (mesalamine) and Flonase (fluticasone propionate). Common drug interactions include depression among females and cardiogenic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Rowasa and Flonase. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Rowasa?

Rowasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 943 Rowasa users. Check the latest studies of Rowasa.

What is Flonase?

Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.

On Aug, 07, 2026

23 people who take Rowasa and Flonase together, and have interactions are studied.

What are the common drug interactions of Rowasa and Flonase, by gender? *:

female:

Depression
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Headache (pain in head)
Inflammatory bowel disease
Malignant melanoma (skin cancer rises from melancytes)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure acute (rapid kidney dysfunction)
Uveitis (inflammation of the uvea)
Myalgia (muscle pain)
Muscular weakness (muscle weakness)

male:

Cardiogenic shock (inadequate circulation of blood)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Cytomegalovirus infection
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Myocarditis (inflammation of heart muscle myocardium)
Peripheral embolism (sudden interruption of blood flow to an organ or body part)
Pneumonia
Septic shock (shock due to blood infection)
Diarrhoea

What are the common drug interactions of Rowasa and Flonase, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Vomiting
Weight decreased
Wheezing (a high-pitched whistling sound made while you breath)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Depression
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Inflammatory bowel disease
Malignant melanoma (skin cancer rises from melancytes)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure acute (rapid kidney dysfunction)

40-49:

Diarrhoea
Gastroenteritis escherichia coli (inflammation of stomach and intestine caused by escherichia coli infection)
Nausea (feeling of having an urge to vomit)
Vomiting
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Dyspnoea (difficult or laboured respiration)
Wheezing (a high-pitched whistling sound made while you breath)

50-59:

Arthralgia (joint pain)
Blood creatinine increased
Blood urea increased
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Depression
Diarrhoea
Dizziness
Fatigue (feeling of tiredness)
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Headache (pain in head)

60+:

Diarrhoea
Abdominal discomfort
Haematochezia (passage of stools containing blood)
Scratch
Urinary tract infection
Abdominal pain
Abdominal pain upper
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Faeces discoloured
Flatulence (flatus expelled through the anus)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 15 people, 65.22%
Upper Respiratory Tract Infection: 11 people, 47.83%
Kidney Infection (Pyelonephritis): 11 people, 47.83%
Depression: 11 people, 47.83%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 47.83%
Acne (skin problems that cause pimples): 11 people, 47.83%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 5 people, 21.74%
Diarrhea: 3 people, 13.04%
Sleep Disorder: 2 people, 8.70%
Immunodeficiency Common Variable: 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Rowasa and Flonase?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously