Rozerem and Epinephrine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rozerem (ramelteon) and Epinephrine (epinephrine). Common drug interactions include headache among females and atrial fibrillation among males.
The phase IV clinical study analyzes what interactions people have when they take Rozerem and Epinephrine. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.
What is Rozerem?
Rozerem has active ingredients of ramelteon. It is often used in insomnia. eHealthMe is studying from 7,539 Rozerem users. Check the latest studies of Rozerem.
What is Epinephrine?
Epinephrine has active ingredients of epinephrine. It is often used in asthma. eHealthMe is studying from 21,290 Epinephrine users. Check the latest studies of Epinephrine.
23 people who take Rozerem and Epinephrine together, and have interactions are studied.

What are the common drug interactions of Rozerem and Epinephrine, by gender? *:
female:
- Headache (pain in head)
- Pain
- Malaise (a feeling of general discomfort or uneasiness)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Fall
- Infusion site extravasation (flow of (blood or lymph) from infusion site)
- Infusion site oedema (swelling from excessive accumulation of watery fluid from infusion site)
- Limb injury
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Cardiac failure congestive
male:
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Localised infection (infection at the single location)
- Seasonal allergy (allergic condition due to certain season)
- Death
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Brain neoplasm malignant (brain cancer tumour)
What are the common drug interactions of Rozerem and Epinephrine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Depression
- Emotional distress
- Injury
- Pain
- Psychological trauma
- Pulmonary embolism (blockage of the main artery of the lung)
40-49:
n/a
50-59:
- Lymphoma (cancer that begins in immune system cells)
- Septic shock (shock due to blood infection)
- Acute respiratory failure
- Anaemia postoperative
- Asthenia (weakness)
- Dyspnoea (difficult or laboured respiration)
- Endocarditis (inflammation in heart muscle)
- Fluid overload (too much fluid in the blood)
- Hypotension (abnormally low blood pressure)
- Influenza like illness
60+:
- Brain neoplasm (tumour of brain)
- Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
- Brain neoplasm malignant (brain cancer tumour)
- Central nervous system lymphoma (cancer of central nervous system forms in lymph tissue)
- Death
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Cardiac failure congestive
- Colostomy
- Cough
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
What are the existing conditions these people have? *
- Stress And Anxiety: 8 people, 34.78%
- Depression: 7 people, 30.43%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 30.43%
- High Blood Pressure: 7 people, 30.43%
- Pain: 7 people, 30.43%
- Nausea (feeling of having an urge to vomit): 7 people, 30.43%
- Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 6 people, 26.09%
- Hypogonadism (reduction or absence of hormone secretion or other physiological activity of the gonads (testes or ovaries)): 6 people, 26.09%
- Constipation: 6 people, 26.09%
- Sleep Disorder: 6 people, 26.09%
* Approximation only. Some reports may have incomplete information.
Do you take Rozerem and Epinephrine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Rozerem (7,539 reports)
- Epinephrine (21,290 reports)
Browse all drug interactions of Rozerem and Epinephrine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rozerem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Epinephrine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rozerem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Epinephrine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ramelteon and epinephrine (the active ingredients of Rozerem and Epinephrine, respectively), and Rozerem and Epinephrine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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