Rybrevant and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rybrevant (amivantamab-vmjw) and Acetaminophen (acetaminophen). Common drug interactions include infusion related reaction among females and generalised oedema among males.

The phase IV clinical study analyzes what interactions people have when they take Rybrevant and Acetaminophen. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Rybrevant?

Rybrevant has active ingredients of amivantamab-vmjw. eHealthMe is studying from 560 Rybrevant users. Check the latest studies of Rybrevant.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Jul, 30, 2026

18 people who take Rybrevant and Acetaminophen together, and have interactions are studied.

Rybrevant and Acetaminophen drug interactions.

What are the common drug interactions of Rybrevant and Acetaminophen, by gender? *:

female:

Infusion related reaction
Nausea (feeling of having an urge to vomit)
Dyspnoea (difficult or laboured respiration)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Dry skin
Oxygen saturation decreased
Peripheral swelling
Somnolence (a state of near-sleep, a strong desire for sleep)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

male:

Generalised oedema (swelling all over the body)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Pleural effusion (water on the lungs)
Pulmonary infarction (death of a small area of lung)
Renal disorder (kidney disease)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Blood pressure increased
Infusion related reaction
Rash
Respiratory rate increased (excess breathing rate/min)

What are the common drug interactions of Rybrevant and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Infusion related reaction
Nausea (feeling of having an urge to vomit)
Constipation
Contusion (a type of hematoma of tissue in which capillaries)
Dry skin
Dyspnoea (difficult or laboured respiration)
Oxygen saturation decreased
Peripheral swelling
Somnolence (a state of near-sleep, a strong desire for sleep)
Erythema (redness of the skin)

60+:

Generalised oedema (swelling all over the body)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Metabolic alkalosis (too much bicarbonate in the blood)
Pleural effusion (water on the lungs)
Pulmonary infarction (death of a small area of lung)
Renal disorder (kidney disease)
Rash
Respiratory failure (inadequate gas exchange by the respiratory system)
Infusion related reaction
Fall

What are the existing conditions these people have? *

Non-Small Cell Lung Cancer Metastatic (type of epithelial lung cancer spreads to other parts): 5 people, 27.78%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 22.22%
Lung Adenocarcinoma (a form of non-small cell lung cancer): 3 people, 16.67%
Non-Small Cell Lung Cancer Stage Iv: 2 people, 11.11%
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking): 2 people, 11.11%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 11.11%
Lung Neoplasm (tumour of lung): 2 people, 11.11%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 11.11%
Abdominal Pain: 2 people, 11.11%
Metastases To Peritoneum (cancer spreads to peritoneum): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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