Rythmol and Gabapentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol (propafenone hydrochloride) and Gabapentin (gabapentin). Common drug interactions include coronary artery disease among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol and Gabapentin. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,983 Gabapentin users. Check the latest studies of Gabapentin.

On Jul, 15, 2026

59 people who take Rythmol and Gabapentin together, and have interactions are studied.

Rythmol and Gabapentin drug interactions.

What are the common drug interactions of Rythmol and Gabapentin, by gender? *:

female:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Drug effect decreased
Dry mouth
Eye infection
Eye pain
Fall
Fatigue (feeling of tiredness)
Gait disturbance
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

male:

Chronic kidney disease
Constipation
Hallucination (an experience involving the perception of something not present)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Back pain
Balance disorder
Chest pain
Dizziness
Dysgeusia (disorder of the sense of taste)
Erectile dysfunction

What are the common drug interactions of Rythmol and Gabapentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Constipation
Depression
Dry mouth
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Spinal disorder (disease of spine a back bone)
Vision blurred
Visual impairment
Weight increased

40-49:

n/a

50-59:

Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Ascites (accumulation of fluid in the abdominal cavity)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiovascular disorder (heart diseases)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Dermatitis allergic (inflammation of the skin due allergic reaction)
Emotional distress

60+:

Chest pain
Drug ineffective
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumonia
Somnolence (a state of near-sleep, a strong desire for sleep)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Back pain
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the existing conditions these people have? *

Pain: 10 people, 16.95%
High Blood Pressure: 9 people, 15.25%
High Blood Cholesterol: 7 people, 11.86%
Multiple Myeloma (cancer of the plasma cells): 7 people, 11.86%
Neuropathy Peripheral (surface nerve damage): 6 people, 10.17%
Sleep Disorder: 4 people, 6.78%
Asthma: 4 people, 6.78%
Stress And Anxiety: 4 people, 6.78%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 6.78%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 3 people, 5.08%

* Approximation only. Some reports may have incomplete information.

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