Rythmol and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol (propafenone hydrochloride) and Reglan (metoclopramide hydrochloride). Common drug interactions include coronary artery disease among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol and Reglan. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

On Jul, 12, 2026

29 people who take Rythmol and Reglan together, and have interactions are studied.

What are the common drug interactions of Rythmol and Reglan, by gender? *:

female:

Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Decreased appetite
Dehydration (dryness resulting from the removal of water)
Asthenia (weakness)
Dysphagia (a condition in which swallowing is difficult or painful)
Anaemia (lack of blood)
Hypophagia (reduced food intake)
Blood glucose decreased
Blood bilirubin increased
Disease recurrence

male:

Asthenia (weakness)
Neuropathy peripheral (surface nerve damage)
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Hypotension (abnormally low blood pressure)
International normalised ratio increased
Malignant neoplasm progression (cancer tumour came back)
Multi-organ failure (multisystem organ failure)
Multiple myeloma (cancer of the plasma cells)
Muscular weakness (muscle weakness)
Pco2 decreased

What are the common drug interactions of Rythmol and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Aortic valve incompetence
Dizziness
Dyspepsia (indigestion)
Ejection fraction decreased (systolic heart failure)
Fatigue (feeling of tiredness)
Heart rate increased
Hypotension (abnormally low blood pressure)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Mitral valve calcification (calcium deposit in mitral valve)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)

40-49:

n/a

50-59:

Syncope (loss of consciousness with an inability to maintain postural tone)
Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
Anxiety
Blood alkaline phosphatase increased
Blood glucose decreased
Blood glucose increased
Blood thyroid stimulating hormone decreased
Cardiac failure congestive
Chest discomfort
Chest pain

60+:

Asthenia (weakness)
Dysphagia (a condition in which swallowing is difficult or painful)
Dry eye (lack of adequate tears)
Dysgeusia (disorder of the sense of taste)
Eye irritation
Eye pain
Haemorrhoidal haemorrhage (bleeding from the haemorrhoids)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypophagia (reduced food intake)
Leukopenia (less number of white blood cells in blood)

What are the existing conditions these people have? *

Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 13.79%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 13.79%
Nausea (feeling of having an urge to vomit): 3 people, 10.34%
Venous Thrombosis (blood clot (thrombus) that forms within a vein): 2 people, 6.90%
Indigestion: 2 people, 6.90%
Breakthrough Pain: 2 people, 6.90%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 6.90%
Constipation: 2 people, 6.90%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 2 people, 6.90%
Cough: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

Do you take Rythmol and Reglan?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously