Ryzodeg 70/30 and Repatha drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ryzodeg 70/30 (insulin aspart; insulin degludec) and Repatha (evolocumab). Common drug interactions include cardio-respiratory arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Ryzodeg 70/30 and Repatha. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Ryzodeg 70/30?

Ryzodeg 70/30 has active ingredients of insulin aspart; insulin degludec. eHealthMe is studying from 713 Ryzodeg 70/30 users. Check the latest studies of Ryzodeg 70/30.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.



On Jul, 12, 2026

21 people who take Ryzodeg 70/30 and Repatha together, and have interactions are studied.

Ryzodeg 70/30 and Repatha drug interactions.

What are the common drug interactions of Ryzodeg 70/30 and Repatha, by gender? *:

female:

n/a

male:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
  5. Hyperkinetic heart syndrome (hyperkinetic heart disease is when the heart is beating faster that it should be)
  6. Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
  7. Hypokinesia (decreased bodily movement)
  8. Akinesia (loss of control of voluntary muscle movements)
  9. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  10. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)

What are the common drug interactions of Ryzodeg 70/30 and Repatha, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  2. Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
  3. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  4. Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
  5. Hyperkinetic heart syndrome (hyperkinetic heart disease is when the heart is beating faster that it should be)
  6. Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
  7. Hypokinesia (decreased bodily movement)
  8. Akinesia (loss of control of voluntary muscle movements)
  9. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  10. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)

60+:

n/a

What are the existing conditions these people have? *

  1. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 21 people, 100.00%
  2. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 15 people, 71.43%
  3. Hyperuricaemia (level of uric acid in the blood that is abnormally high): 2 people, 9.52%
  4. Hyperlipidaemia (presence of excess lipids in the blood): 2 people, 9.52%
  5. High Blood Pressure: 2 people, 9.52%
  6. Diabetes: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Ryzodeg 70/30 and Repatha?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ryzodeg 70/30 and Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ryzodeg 70/30:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ryzodeg 70/30 and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Repatha and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on insulin aspart; insulin degludec and evolocumab (the active ingredients of Ryzodeg 70/30 and Repatha, respectively), and Ryzodeg 70/30 and Repatha (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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