Senna and Rocephin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Senna (senna) and Rocephin (ceftriaxone sodium). Common drug interactions include asthenia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Senna and Rocephin. It is created by eHealthMe based on reports of 93 people who take the same drugs from the FDA, and is updated regularly.

What is Senna?

Senna has active ingredients of senna. It is often used in constipation. eHealthMe is studying from 37,302 Senna users. Check the latest studies of Senna.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

On Jul, 19, 2026

93 people who take Senna and Rocephin together, and have interactions are studied.

What are the common drug interactions of Senna and Rocephin, by gender? *:

female:

Asthenia (weakness)
Back pain
Dental caries
Neuropathy peripheral (surface nerve damage)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Osteonecrosis of jaw (death of bone of jaw)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Pyrexia (fever)
Tremor (trembling or shaking movements in one or more parts of your body)

male:

Febrile neutropenia (fever with reduced white blood cells)
Pain
Muscular weakness (muscle weakness)
Myalgia (muscle pain)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Pyrexia (fever)
Scar
Skin lesion
Skin tightness
Skin ulcer

What are the common drug interactions of Senna and Rocephin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hypertension (high blood pressure)

10-19:

Asthenia (weakness)
Bacterial infection
C-reactive protein increased
Decreased appetite
Drug ineffective
Inflammation
Pancreatitis (inflammation of pancreas)
Rash papular (redness with papule)
Rash pruritic (redness with itching)
Skin exfoliation (removal of the oldest dead skin cells)

20-29:

Chronic kidney disease
Emotional distress
Haematoma (collection of blood outside the blood vessels)
Pain
Renal failure (kidney dysfunction)

30-39:

Chronic kidney disease
Dyspepsia (indigestion)
Gastritis (inflammation of stomach)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Seasonal allergy (allergic condition due to certain season)
Upper respiratory tract inflammation
Alopecia (absence of hair from areas of the body)
Asthma
Body tinea (ringworm of the body)
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)

40-49:

Arthralgia (joint pain)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Abdominal pain
Anxiety
Dyskinesia (abnormality or impairment of voluntary movement)
Emotional distress
Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)
Myalgia (muscle pain)

50-59:

Cough
Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
Hepatic enzyme increased
Herpes zoster
Hypoaesthesia (reduced sense of touch or sensation)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Large intestinal obstruction
Leukocytosis (increased white blood cells)
Lung infection
Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)

60+:

Pyrexia (fever)
Lethargy (tiredness)
Anxiety
Atelectasis (partial or complete collapse of the lung)
Blindness unilateral
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Gait disturbance
Headache (pain in head)
Onychomycosis (fungal infection of the nail)

What are the existing conditions these people have? *

Stress And Anxiety: 13 people, 13.98%
Pain: 13 people, 13.98%
Nausea (feeling of having an urge to vomit): 13 people, 13.98%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 11.83%
Indigestion: 8 people, 8.60%
Sinusitis (inflammation of sinus): 7 people, 7.53%
Urinary Tract Infection: 6 people, 6.45%
Fever: 6 people, 6.45%
Asthma: 6 people, 6.45%
Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 5 people, 5.38%

* Approximation only. Some reports may have incomplete information.

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