Seroquel and Acthar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Acthar (corticotropin). Common drug interactions include headache among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Seroquel and Acthar. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.

What is Acthar?

Acthar has active ingredients of corticotropin. eHealthMe is studying from 4,948 Acthar users. Check the latest studies of Acthar.

On Aug, 09, 2026

14 people who take Seroquel and Acthar together, and have interactions are studied.

What are the common drug interactions of Seroquel and Acthar, by gender? *:

female:

Headache (pain in head)
Abdominal mass (localized enlargement or swelling in the human abdomen)
Abdominal pain
Back pain
Blood iron decreased
Cervix carcinoma (cancer of cervix)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Dyspnoea (difficult or laboured respiration)

male:

Fatigue (feeling of tiredness)
Abdominal distension
Pyrexia (fever)
Abdominal pain
Herpes zoster
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Rash
Sinusitis (inflammation of sinus)
Injection site erythema (redness at injection site)

What are the common drug interactions of Seroquel and Acthar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)
Influenza like illness
Psychomotor hyperactivity (feelings of extreme restlessness)
Sleep disorder
Swelling face
Tachyphrenia (abnormally rapid mental activity)
Headache (pain in head)
Injection site erythema (redness at injection site)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)

40-49:

Abdominal mass (localized enlargement or swelling in the human abdomen)
Abdominal pain
Back pain
Blood iron decreased
Cervix carcinoma (cancer of cervix)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Contusion (a type of hematoma of tissue in which capillaries)
Diarrhoea
Gait disturbance
Headache (pain in head)

50-59:

Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

60+:

Fatigue (feeling of tiredness)
Abdominal distension
Abdominal pain
Herpes zoster
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Rash
Sinusitis (inflammation of sinus)
Pain

What are the existing conditions these people have? *

Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 5 people, 35.71%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 21.43%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 14.29%
Sarcoidosis (an inflammatory disease that affects multiple organs in the body, but mostly the lungs and lymph glands): 1 person, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.14%
Multiple Sclerosis Relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 7.14%
Mixed Connective Tissue Disease (an autoimmune disease, in which the body's defence system attacks itself): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Seroquel and Acthar?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously