Seroquel and Ephedrine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Seroquel (quetiapine fumarate) and Ephedrine (ephedra). Common drug interactions include hypertension among females and dizziness among males.
The phase IV clinical study analyzes what interactions people have when they take Seroquel and Ephedrine. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
What is Ephedrine?
Ephedrine has active ingredients of ephedra. It is often used in weight loss. eHealthMe is studying from 1,763 Ephedrine users. Check the latest studies of Ephedrine.
21 people who take Seroquel and Ephedrine together, and have interactions are studied.

What are the common drug interactions of Seroquel and Ephedrine, by gender? *:
female:
- Hypertension (high blood pressure)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Red blood cell sedimentation rate increased
- Reproductive tract disorder (disease of reproductive system)
- Road traffic accident
- Suicide attempt
- White blood cell count increased
- Gastrointestinal disorder (functional problems of gastrointestinal tract)
- Type 2 diabetes mellitus
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
male:
- Dizziness
- Suicidal ideation
- Emotional disorder
- Emotional distress
- Feeling of despair
- General physical health deterioration (weak health status)
- Hostility
- Hyperhidrosis (abnormally increased sweating)
- Impaired driving ability
- Impaired reasoning
What are the common drug interactions of Seroquel and Ephedrine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Blood triglycerides increased
- C-reactive protein increased
- Gallbladder disorder
- Hypertension (high blood pressure)
- Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
- Red blood cell sedimentation rate increased
- Reproductive tract disorder (disease of reproductive system)
- Road traffic accident
30-39:
- Blood insulin increased
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
- Infertility
- Ovarian cyst (fluid filled sac of the ovary)
- Polycystic ovaries (cysts in the ovaries that occurs when the follicle stops developing)
- Sedation
- Thyroid disorder (thyroid diseases)
- Type 2 diabetes mellitus
- Vision blurred
40-49:
- Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
- Polyuria (production of too much dilute urine)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Type 2 diabetes mellitus
- Erectile dysfunction
- Multiple drug overdose accidental
- Antisocial personality disorder
- Blood cholesterol increased
- Diabetes mellitus inadequate control
- Diabetic nephropathy (diabetic kidney disease)
50-59:
n/a
60+:
- Abulia (lack of will or initiative)
- Anger
- Constipation
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Death
- Decreased interest
- Depressed mood
- Dizziness
- Drug dependence
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
What are the existing conditions these people have? *
- Insomnia (sleeplessness): 11 people, 52.38%
- Pain: 9 people, 42.86%
- Sleep Disorder: 8 people, 38.10%
- Depression: 5 people, 23.81%
- Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 3 people, 14.29%
- Dissociation: 3 people, 14.29%
- Borderline Personality Disorder: 3 people, 14.29%
- Schizophrenia, Paranoid Type (delusions and auditory hallucinations but relatively normal intellectual functioning and expression of affect): 2 people, 9.52%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Seroquel and Ephedrine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Seroquel and Ephedrine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ephedrine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ephedrine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on quetiapine fumarate and ephedra (the active ingredients of Seroquel and Ephedrine, respectively), and Seroquel and Ephedrine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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