Sertraline and Prelone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sertraline (sertraline hydrochloride) and Prelone (prednisolone). Common drug interactions include abdominal pain upper among females and abdominal discomfort among males.
The phase IV clinical study analyzes what interactions people have when they take Sertraline and Prelone. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.
What is Sertraline?
Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.
What is Prelone?
Prelone has active ingredients of prednisolone. It is often used in asthma. eHealthMe is studying from 869 Prelone users. Check the latest studies of Prelone.
17 people who take Sertraline and Prelone together, and have interactions are studied.

What are the common drug interactions of Sertraline and Prelone, by gender? *:
female:
- Abdominal pain upper
- Dyspnoea (difficult or laboured respiration)
- Herpes virus infection
- Wheezing (a high-pitched whistling sound made while you breath)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Asthmatic crisis
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Insomnia (sleeplessness)
- Lung disorder (lung disease)
- Weight decreased
male:
- Abdominal discomfort
- Blood pressure decreased
- Blood pressure increased
- Dizziness
- Glossodynia (a burning or painful sensation in the tongue)
What are the common drug interactions of Sertraline and Prelone, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Urinary tract infection
- Abdominal pain upper
- Erysipelas (bacterial skin infection)
- Fall
- Fatigue (feeling of tiredness)
- Herpes virus infection
- Ill-defined disorder
- Inflammation
- Influenza
- Joint swelling
50-59:
- Weight decreased
- Adrenal adenoma (benign tumour of the glandular type (adenoma) in the adrenal gland)
- Sinusitis (inflammation of sinus)
- Wound
- Cushingoid (obesity and weakening of the muscles)
- Hypersensitivity
- Osteoporosis (bones weak and more likely to break)
- Pain in extremity
- Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
- Weight increased
60+:
- Dyspnoea (difficult or laboured respiration)
- Wheezing (a high-pitched whistling sound made while you breath)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Drug ineffective
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Emotional disorder
- Gait disturbance
- Gallbladder disorder
- General physical health deterioration (weak health status)
What are the existing conditions these people have? *
- High Blood Pressure: 9 people, 52.94%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 7 people, 41.18%
- Stress And Anxiety: 4 people, 23.53%
- Sleep Disorder: 4 people, 23.53%
- Osteoporosis (bones weak and more likely to break): 3 people, 17.65%
- Pain: 3 people, 17.65%
- Gastric Polyps (abnormal growth of stomach tissue projecting from a mucous membrane): 2 people, 11.76%
- Cardiac Failure: 2 people, 11.76%
- Liver Disorder (liver diseases): 2 people, 11.76%
- Hypersensitivity: 2 people, 11.76%
* Approximation only. Some reports may have incomplete information.
Do you take Sertraline and Prelone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Sertraline (153,304 reports)
- Prelone (869 reports)
Browse all drug interactions of Sertraline and Prelone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sertraline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Prelone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sertraline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Prelone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
- Abdullah, D., Mohamed, A. M. F. S., & Liew, A. K. C., "Dentine hypersensitivity-like tooth pain associated with the use of high-dose steroid therapy", Journal of conservative dentistry: JCD, 2018 Jan .
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sertraline hydrochloride and prednisolone (the active ingredients of Sertraline and Prelone, respectively), and Sertraline and Prelone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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