Prozac and Application site swelling - a phase IV clinical study of FDA data

Summary:

Application site swelling is reported as a side effect among people who take Prozac (fluoxetine hydrochloride), especially for people who are female, 20-29 old, also take Gilenya, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Application site swelling when taking Prozac. It is created by eHealthMe based on reports of 74,788 people who have side effects when taking Prozac from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Application site swelling?

Application site swelling is found to be associated with 220 drugs and 477 conditions by eHealthMe. Check the latest studies of Application site swelling.

On Jul, 17, 2026

74,788 people reported to have side effects when taking Prozac.
Among them, 15 people (0.02%) have Application site swelling.

Could Prozac cause Application site swelling?

Among these 15 people:

What is the gender of people who have Application site swelling when taking Prozac? *

female: 84.62 %
male: 15.38 %

What is the age of people who have Application site swelling when taking Prozac? *

What are other drugs people take besides Prozac? *

What are other side effects people have besides Application site swelling? *

Application Site Pruritus (application site severe itching of the skin): 10 people, 66.67%
Gait Disturbance: 6 people, 40.00%
Upper Respiratory Tract Infection: 6 people, 40.00%
Staring (a prolonged gaze or fixed look): 6 people, 40.00%
Nausea And Vomiting: 6 people, 40.00%
Lymphocyte Count Decreased: 5 people, 33.33%
Red Blood Cell Count Increased: 5 people, 33.33%
Application Site Erythema (redness of the skin at application site): 5 people, 33.33%
Nausea (feeling of having an urge to vomit): 5 people, 33.33%
Nasopharyngitis (inflammation of the nasopharynx): 4 people, 26.67%

What are the existing conditions these people have? *

Pain: 6 people, 40.00%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 40.00%
Tic (a sudden, repetitive, nonrhythmic motor movement or vocalization involving discrete muscle groups): 1 person, 6.67%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 6.67%
Precancerous Skin Lesion: 1 person, 6.67%
Parkinson's Disease: 1 person, 6.67%
Night Sweats (sweating in night): 1 person, 6.67%
Hot Flush (sudden feelings of heat): 1 person, 6.67%
Heavy Exposure To Ultraviolet Light: 1 person, 6.67%
Bipolar Disorder (mood disorder): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Prozac and have Application site swelling?

- Check whether Application site swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prozac:

Prozac (82,988 reports)

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site swelling:

Application site swelling (220 drugs)

Browse all the conditions that are associated with Application site swelling:

Application site swelling (477 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Prozac) and Prozac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.