Signifor lar and Amlodipine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Signifor lar (pasireotide pamoate) and Amlodipine (amlodipine besylate). Common drug interactions include dyspnoea exertional among females and hyperglycaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Signifor lar and Amlodipine. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Signifor lar?

Signifor lar has active ingredients of pasireotide pamoate. eHealthMe is studying from 1,198 Signifor lar users. Check the latest studies of Signifor lar.

What is Amlodipine?

Amlodipine has active ingredients of amlodipine besylate. It is often used in high blood pressure. eHealthMe is studying from 354,829 Amlodipine users. Check the latest studies of Amlodipine.

On Jul, 17, 2026

55 people who take Signifor lar and Amlodipine together, and have interactions are studied.

Signifor lar and Amlodipine drug interactions.

What are the common drug interactions of Signifor Lar and Amlodipine, by gender? *:

female:

Dyspnoea exertional (breathlessness or shortness of breath)
Dysuria (painful or difficult urination)
Frequent bowel movements
Injection site pain
Injection site vesicles (fluid- or air-filled cavity or sac at injection site)
Pain
Uterine haemorrhage (uterine bleeding)
Uterine mass
Uterine polyp (a mass in the inner lining of the uterus)
Vaginal haemorrhage (vaginal bleeding)

male:

Hyperglycaemia (high blood sugar)
Hyperkalaemia (damage to or disease of the kidney)
Vomiting
Fatigue (feeling of tiredness)
Dry mouth
Haemoglobin decreased
Diverticulum intestinal haemorrhagic (a pouch that is attached to the first part of the small intestine with bleeding)
Gastrointestinal infection (infection of stomach and intestine)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Melaena (the passage of black, tarry stools)

What are the common drug interactions of Signifor Lar and Amlodipine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Fatigue (feeling of tiredness)

50-59:

Dry mouth
Fatigue (feeling of tiredness)
Blood glucose increased
Dizziness
Hyperglycaemia (high blood sugar)
Nausea (feeling of having an urge to vomit)
Polydipsia (excessive thirst)
Polyuria (production of too much dilute urine)
Vision blurred
Haemoglobin decreased

60+:

Hyperglycaemia (high blood sugar)
Blood glucose increased
Blindness
Blood glucose decreased
Blood pressure decreased
Blood pressure fluctuation
Blood urea increased
Dry skin
Fall
Head injury

What are the existing conditions these people have? *

Acromegaly (body produces too much growth hormone, leading to excess growth of body tissues): 39 people, 70.91%
Type 2 Diabetes: 15 people, 27.27%
Parkinson's Disease: 10 people, 18.18%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 18.18%
Pituitary-Dependent Cushing's Syndrome (pituitary dependent hypercortisolism): 9 people, 16.36%
Gigantism (excessive growth and height): 6 people, 10.91%
Hypovitaminosis (any of several diseases caused by deficiency of one or more vitamins): 5 people, 9.09%
Pituitary Tumor: 4 people, 7.27%
Nasopharyngeal Cancer (cancer of nasopharynx): 4 people, 7.27%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 7.27%

* Approximation only. Some reports may have incomplete information.

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