Sildenafil citrate and Xeljanz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sildenafil citrate (sildenafil citrate) and Xeljanz (tofacitinib citrate). Common drug interactions include headache among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Sildenafil citrate and Xeljanz. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Sildenafil citrate?

Sildenafil citrate has active ingredients of sildenafil citrate. It is often used in erection problems. eHealthMe is studying from 23,013 Sildenafil citrate users. Check the latest studies of Sildenafil citrate.

What is Xeljanz?

Xeljanz has active ingredients of tofacitinib citrate. It is often used in rheumatoid arthritis. eHealthMe is studying from 239,081 Xeljanz users. Check the latest studies of Xeljanz.

On Aug, 02, 2026

34 people who take Sildenafil citrate and Xeljanz together, and have interactions are studied.

Sildenafil citrate and Xeljanz drug interactions.

What are the common drug interactions of Sildenafil Citrate and Xeljanz, by gender? *:

female:

Headache (pain in head)
Fatigue (feeling of tiredness)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Fall
Pneumonia
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Ankle fracture
Endometrial cancer
Malaise (a feeling of general discomfort or uneasiness)

male:

Drug ineffective
Joint swelling
Breath sounds
Cellulitis (infection under the skin)
Diarrhoea
Dizziness
Dry eye (lack of adequate tears)
Dry mouth
Dyspnoea (difficult or laboured respiration)
Frequent bowel movements

What are the common drug interactions of Sildenafil Citrate and Xeljanz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dyspnoea (difficult or laboured respiration)
Malaise (a feeling of general discomfort or uneasiness)

40-49:

Pain
Anxiety
Depression
Dry eye (lack of adequate tears)
Dry mouth
Grip strength decreased
Herpes zoster
Malaise (a feeling of general discomfort or uneasiness)
Photosensitivity reaction
Rash

50-59:

Influenza
Blood cholesterol increased
Diarrhoea
Drug ineffective
Frequent bowel movements
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Joint swelling
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pain
Pain in extremity

60+:

Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Death
Dizziness
Respiratory moniliasis (fungal infection of respiratory system)
Rhinorrhoea (watery mucus discharge from the nose)
Abscess (pus)
Animal scratch
Arthralgia (joint pain)
Back pain

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 9 people, 26.47%
Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 3 people, 8.82%
Myositis (inflammation of the muscles): 3 people, 8.82%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 5.88%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 5.88%
Morphea: 2 people, 5.88%
Chest Pain: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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