Simcor and Clonazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Simcor (niacin; simvastatin) and Clonazepam (clonazepam). Common drug interactions include blood glucose increased among females and flushing among males.
The phase IV clinical study analyzes what interactions people have when they take Simcor and Clonazepam. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.
What is Simcor?
Simcor has active ingredients of niacin; simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 11,604 Simcor users. Check the latest studies of Simcor.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,272 Clonazepam users. Check the latest studies of Clonazepam.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
70 people who take Simcor and Clonazepam together, and have interactions are studied.

What are the common drug interactions of Simcor and Clonazepam, by gender? *:
female:
- Blood glucose increased
- Skin burning sensation
- Abdominal pain upper
- Arthralgia (joint pain)
- Burning sensation
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
- Rash
- Abdominal distension
male:
- Flushing (the warm, red condition of human skin)
- Blood glucose increased
- Blood creatinine increased
- Constipation
- Haematochezia (passage of stools containing blood)
- Knee arthroplasty
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Procedural pain
- Tremor (trembling or shaking movements in one or more parts of your body)
- Acne (skin problems that cause pimples)
What are the common drug interactions of Simcor and Clonazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Flushing (the warm, red condition of human skin)
- Cardiac ventricular disorder (ventricular dysfunction of heart)
- Chest pain
- Fall
- Feeling hot
- Insomnia (sleeplessness)
- Joint swelling
- Muscle spasms (muscle contraction)
- Oedema peripheral (superficial swelling)
- Pharyngeal oedema (abnormal accumulation of fluid in the cavities and intercellular spaces of the pharyngeal)
40-49:
- Flushing (the warm, red condition of human skin)
- Headache (pain in head)
- Pruritus (severe itching of the skin)
- Conjunctivitis infective (infection of the conjunctiva)
- Feeling hot
- Muscle tightness
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Sedation
- Skin burning sensation
- Swelling
50-59:
- Pruritus (severe itching of the skin)
- Flushing (the warm, red condition of human skin)
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Blood glucose increased
- Erythema (redness of the skin)
- Abdominal discomfort
- Diarrhoea
- Headache (pain in head)
- Insomnia (sleeplessness)
- Nausea (feeling of having an urge to vomit)
60+:
- Flushing (the warm, red condition of human skin)
- Constipation
- Breast cancer
- Dyspnoea exertional (breathlessness or shortness of breath)
- Erythema (redness of the skin)
- Fatigue (feeling of tiredness)
- Muscular weakness (muscle weakness)
- Nausea (feeling of having an urge to vomit)
- Urine output decreased
- Ear discomfort
What are the existing conditions these people have? *
- Low Density Lipoprotein Increased (cholesterol increased in blood): 12 people, 17.14%
- Depression: 11 people, 15.71%
- High Density Lipoprotein Decreased: 10 people, 14.29%
- High Blood Pressure: 7 people, 10.00%
- Diabetes: 7 people, 10.00%
- Insomnia (sleeplessness): 6 people, 8.57%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 5.71%
- Hypersensitivity: 4 people, 5.71%
* Approximation only. Some reports may have incomplete information.
Do you take Simcor and Clonazepam?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Simcor (11,604 reports)
- Clonazepam (146,272 reports)
Browse all drug interactions of Simcor and Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Simcor:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Simcor and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on niacin; simvastatin and clonazepam (the active ingredients of Simcor and Clonazepam, respectively), and Simcor and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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