Simponi aria and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simponi aria (golimumab) and Acetaminophen (acetaminophen). Common drug interactions include fatigue among females.

The phase IV clinical study analyzes what interactions people have when they take Simponi aria and Acetaminophen. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Simponi aria?

Simponi aria has active ingredients of golimumab. eHealthMe is studying from 3,704 Simponi aria users. Check the latest studies of Simponi aria.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.



On Aug, 10, 2026

16 people who take Simponi aria and Acetaminophen together, and have interactions are studied.

Simponi aria and Acetaminophen drug interactions.

What are the common drug interactions of Simponi Aria and Acetaminophen, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Infusion site swelling
  3. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  4. Chest pain
  5. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  6. Diarrhoea
  7. Herpes zoster
  8. Pain in extremity
  9. Respiratory tract infection
  10. Weight decreased

male:

n/a

What are the common drug interactions of Simponi Aria and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

30-39:

n/a

40-49:

  1. Fatigue (feeling of tiredness)
  2. Gastric bypass
  3. Infusion site discomfort
  4. Infusion site induration
  5. Infusion site swelling
  6. Sinusitis (inflammation of sinus)
  7. Urinary tract infection
  8. Hypersensitivity
  9. Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)

50-59:

  1. Abdominal tenderness
  2. Anxiety
  3. Arthralgia (joint pain)
  4. Asthenia (weakness)
  5. Back pain
  6. Constipation
  7. Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
  8. Dizziness
  9. Dyspnoea (difficult or laboured respiration)
  10. Fall

60+:

  1. Obstruction
  2. Limb injury
  3. Hospitalisation
  4. Abdominal pain
  5. Acute myocardial infarction (acute heart attack)
  6. Acute respiratory failure
  7. Arthralgia (joint pain)
  8. Atrioventricular block (heart block)
  9. Back pain
  10. Balance disorder

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 6 people, 37.50%
  2. Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 4 people, 25.00%
  3. Immunodeficiency: 3 people, 18.75%
  4. Chronic Inflammatory Demyelinating Polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord): 3 people, 18.75%
  5. Hypogammaglobulinaemia (an abnormally low concentration of gamma globulin in the blood and increased risk of infection): 3 people, 18.75%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 12.50%
  7. Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 2 people, 12.50%
  8. Immune System Disorder: 2 people, 12.50%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  10. Heart Palpitations (feelings or sensations that your heart is pounding or racing): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Simponi aria and Acetaminophen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Simponi aria and Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simponi aria:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Acetaminophen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simponi aria and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acetaminophen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on golimumab and acetaminophen (the active ingredients of Simponi aria and Acetaminophen, respectively), and Simponi aria and Acetaminophen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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