Simponi and Vitamin b3 drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Simponi (golimumab) and Vitamin b3 (niacin). Common drug interactions include drug hypersensitivity among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Simponi and Vitamin b3. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Simponi?
Simponi has active ingredients of golimumab. It is often used in rheumatoid arthritis. eHealthMe is studying from 86,328 Simponi users. Check the latest studies of Simponi.
What is Vitamin b3?
Vitamin b3 has active ingredients of niacin. It is often used in energy increased. eHealthMe is studying from 1,907 Vitamin b3 users. Check the latest studies of Vitamin b3.
13 people who take Simponi and Vitamin b3 together, and have interactions are studied.

What are the common drug interactions of Simponi and Vitamin B3, by gender? *:
female:
- Drug hypersensitivity
- Drug intolerance (drug sensitivity)
- Dry mouth
- Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
- Weight increased
- Lower respiratory tract infection
- Lung disorder (lung disease)
- Mobility decreased (ability to move is reduced)
- Muscle injury
- Nasopharyngitis (inflammation of the nasopharynx)
male:
- Arthralgia (joint pain)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Pathogen resistance
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Infection
- Knee arthroplasty
- Pain
- Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
- Restless legs syndrome (a powerful urge to move your legs)
What are the common drug interactions of Simponi and Vitamin B3, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Drug ineffective
- Maternal exposure before pregnancy (use of substance before pregnancy)
- Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
40-49:
- Dizziness
- Drug hypersensitivity
- Drug intolerance (drug sensitivity)
- Dry mouth
- Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
- Fatigue (feeling of tiredness)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Lower respiratory tract infection
- Lung disorder (lung disease)
- Mobility decreased (ability to move is reduced)
50-59:
n/a
60+:
- Arthralgia (joint pain)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Fall
- Inflammation
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Endocarditis (inflammation in heart muscle)
- Pathogen resistance
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Infection
What are the existing conditions these people have? *
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 7 people, 53.85%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 4 people, 30.77%
- Psoriasis (immune-mediated disease that affects the skin): 4 people, 30.77%
- Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 15.38%
- Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 7.69%
- Inflammation: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Simponi and Vitamin b3?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Simponi (86,328 reports)
- Vitamin b3 (1,907 reports)
Browse all drug interactions of Simponi and Vitamin b3:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Simponi:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vitamin b3:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Simponi and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vitamin b3 and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
- Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
- Azuma N, Matsui K, Hashimoto N, Yoshikawa T, Sano H, "Successful Switch to Golimumab for Eosinophilia and Skin Symptoms Related to Multiple Biologics in a Patient with Rheumatoid Arthritis", Internal Medicine, 2017 Jun .
- Loebl T, Raskin S, "A novel case report: acute manic psychotic episode after treatment with niacin", The Journal of neuropsychiatry and clinical neurosciences, 2013 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on golimumab and niacin (the active ingredients of Simponi and Vitamin b3, respectively), and Simponi and Vitamin b3 (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Zocor cause Maculopathy? - 5 seconds ago
- Famotidine and Cough for Men aged 30-39 - 9 seconds ago
- Famotidine and Coughing for Men aged 30-39 - 10 seconds ago
- Drug interactions of Timoptic and Centrum - 11 seconds ago
- Could Rifaximin cause Hepatic Failure? - 13 seconds ago
- Could Aricept cause Catatonia? - 13 seconds ago
- Drug interactions of Chlor-Trimeton and Taxotere - 20 seconds ago
- Drug interactions of Voltaren and Ammonium Lactate - 21 seconds ago
- Magnesium and Skin Hemorrhages for Men aged 60+ - 22 seconds ago
- Magnesium and Blood Spots for Men aged 60+ - 23 seconds ago