Simvastatin and Duricef drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Duricef (cefadroxil/cefadroxil hemihydrate). Common drug interactions include dizziness among females and actinic keratosis among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Duricef. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Duricef?

Duricef has active ingredients of cefadroxil/cefadroxil hemihydrate. eHealthMe is studying from 579 Duricef users. Check the latest studies of Duricef.



On Aug, 01, 2026

21 people who take Simvastatin and Duricef together, and have interactions are studied.

Simvastatin and Duricef drug interactions.

What are the common drug interactions of Simvastatin and Duricef, by gender? *:

female:

  1. Dizziness
  2. Drug hypersensitivity
  3. Flushing (the warm, red condition of human skin)
  4. Furuncle (infection of the hair follicle)
  5. Gait disturbance
  6. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  7. Kidney infection
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Mobility decreased (ability to move is reduced)
  10. Muscle spasms (muscle contraction)

male:

  1. Actinic keratosis (skin disease due to sun exposure)
  2. Adenoma benign (non-cancerous tumour -secreting)
  3. Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
  4. Neuropathy peripheral (surface nerve damage)
  5. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Polyp
  8. Rectal haemorrhage (bleeding from anus)
  9. Telangiectasia (small dilated blood vessels near the surface of the skin)
  10. Anhedonia (inability to experience pleasure from activities usually found enjoyable)

What are the common drug interactions of Simvastatin and Duricef, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Death
  2. Neutropenia (an abnormally low number of neutrophils)
  3. White blood cell count increased

50-59:

  1. Nodule (a growth of abnormal tissue)
  2. Pain
  3. Pain in extremity
  4. Productive cough
  5. Sinusitis (inflammation of sinus)
  6. Tenosynovitis (inflammation of the fluid-filled sheath (called the synovium) that surrounds a tendon)
  7. Tinnitus (a ringing in the ears)
  8. Abscess (pus)
  9. Arthralgia (joint pain)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

60+:

  1. Depression
  2. Chronic kidney disease
  3. Diabetes mellitus inadequate control
  4. Emotional distress
  5. Hyperhidrosis (abnormally increased sweating)
  6. Hypokalaemia (low potassium)
  7. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  8. Occult blood positive
  9. Pain
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

What are the existing conditions these people have? *

  1. High Blood Pressure: 6 people, 28.57%
  2. Pain: 6 people, 28.57%
  3. Stress And Anxiety: 5 people, 23.81%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 19.05%
  5. Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 14.29%
  6. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 3 people, 14.29%
  7. Diabetes: 3 people, 14.29%
  8. Dyspnea (difficult or laboured breathing): 3 people, 14.29%
  9. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
  10. High Density Lipoprotein Decreased: 3 people, 14.29%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and Duricef?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Simvastatin and Duricef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Duricef:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simvastatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Duricef and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin and cefadroxil/cefadroxil hemihydrate (the active ingredients of Simvastatin and Duricef, respectively), and Simvastatin and Duricef (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: