Simvastatin and Dynacirc drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Dynacirc (isradipine). Common drug interactions include visual acuity reduced among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Dynacirc. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

What is Dynacirc?

Dynacirc has active ingredients of isradipine. eHealthMe is studying from 975 Dynacirc users. Check the latest studies of Dynacirc.

On Jul, 29, 2026

30 people who take Simvastatin and Dynacirc together, and have interactions are studied.

Simvastatin and Dynacirc drug interactions.

What are the common drug interactions of Simvastatin and Dynacirc, by gender? *:

female:

Visual acuity reduced (reduced clearness of vision)
Abdominal pain
Abdominal pain upper
Acidosis (build-up of carbon dioxide in the blood)
Hyperkalaemia (damage to or disease of the kidney)
Hyperlipidaemia (presence of excess lipids in the blood)
Multiple injuries
Nephritis (inflammation of the nephrons in the kidneys)
Renal failure acute (rapid kidney dysfunction)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

male:

Weight decreased
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Erectile dysfunction
Gynaecomastia (enlargement of the gland tissue of the male breast)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Mitral valve incompetence (inefficient heart valve)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

What are the common drug interactions of Simvastatin and Dynacirc, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Blindness
Blood glucose increased
Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Drug ineffective
Glaucoma (increased fluid pressure in the eye with vision loss)
Renal failure (kidney dysfunction)

40-49:

n/a

50-59:

Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diastolic dysfunction
Fatigue (feeling of tiredness)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Left ventricular hypertrophy (the thickening of the myocardium (muscle) of the left ventricle of the heart)
Nephrolithiasis (calculi in the kidneys)
Palpitations (feelings or sensations that your heart is pounding or racing)
Retching (strong involuntary effort to vomit)
Back injury
Cardiomyopathy (weakening of the heart muscle)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Dizziness
Visual field defect
Coagulopathy (blood's ability to clot is impaired)
Fall
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
Heart rate increased
Injury
Traumatic haematoma (a blood clot in body due to trauma)

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 20.00%
High Blood Pressure: 4 people, 13.33%
Cardiac Failure Congestive: 4 people, 13.33%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 6.67%
Pain: 2 people, 6.67%
Indigestion: 2 people, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 6.67%
Constipation: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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