Simvastatin and Echinacea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Echinacea (echinacea). Common drug interactions include arteriosclerosis among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Echinacea. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

What is Echinacea?

Echinacea has active ingredients of echinacea. It is often used in immune response. eHealthMe is studying from 1,930 Echinacea users. Check the latest studies of Echinacea.

On Jul, 09, 2026

97 people who take Simvastatin and Echinacea together, and have interactions are studied.

Simvastatin and Echinacea drug interactions.

What are the common drug interactions of Simvastatin and Echinacea, by gender? *:

female:

Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Blood pressure decreased
Body temperature increased
Bone pain
Bradycardia (abnormally slow heart action)
Cardiac enzymes increased
Cardiac failure congestive

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug intolerance (drug sensitivity)
Ejaculation failure
Erectile dysfunction

What are the common drug interactions of Simvastatin and Echinacea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Anxiety
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Confusional state
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Diarrhoea
Dizziness
Drug hypersensitivity
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)

50-59:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic microangiopathy (small blood vessels of the body are damaged due to diabetes)
Dry throat
Fall
Headache (pain in head)
Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
Hypoaesthesia (reduced sense of touch or sensation)

60+:

Thrombosis (formation of a blood clot inside a blood vessel)
Chronic kidney disease
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Nephrogenic anaemia (anaemia due to kidney disease)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Anaemia postoperative
Asthma
Back pain
Drug hypersensitivity
Nausea (feeling of having an urge to vomit)

What are the existing conditions these people have? *

Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 29 people, 29.90%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 10.31%
Osteoporosis (bones weak and more likely to break): 9 people, 9.28%
Migraine (headache): 8 people, 8.25%
Infection: 8 people, 8.25%
Cardiac Disorder: 7 people, 7.22%
Depression: 6 people, 6.19%
Urination - Excessive Volume: 5 people, 5.15%
Pain: 5 people, 5.15%

* Approximation only. Some reports may have incomplete information.

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