Simvastatin and Gablofen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Gablofen (baclofen). Common drug interactions include agitation among females and agitation among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Gablofen. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Gablofen?

Gablofen has active ingredients of baclofen. eHealthMe is studying from 3,044 Gablofen users. Check the latest studies of Gablofen.



On Aug, 05, 2026

13 people who take Simvastatin and Gablofen together, and have interactions are studied.

Simvastatin and Gablofen drug interactions.

What are the common drug interactions of Simvastatin and Gablofen, by gender? *:

female:

  1. Agitation (state of anxiety or nervous excitement)
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Burning sensation
  5. Dry mouth
  6. Feeling cold
  7. Hypoaesthesia (reduced sense of touch or sensation)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Device dislocation
  10. Implant site infection

male:

  1. Agitation (state of anxiety or nervous excitement)
  2. Arrhythmia (irregular heartbeat)
  3. Sepsis (a severe blood infection that can lead to organ failure and death)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Urinary tract infection
  6. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  7. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  8. Hallucination (an experience involving the perception of something not present)
  9. Gait disturbance
  10. Granuloma (a small area of inflammation due to tissue injury)

What are the common drug interactions of Simvastatin and Gablofen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Device dislocation
  2. Implant site infection
  3. Muscular weakness (muscle weakness)

50-59:

  1. Limb discomfort (discomfort in leg)
  2. Muscle spasms (muscle contraction)
  3. Pain
  4. Pyrexia (fever)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Somnolence (a state of near-sleep, a strong desire for sleep)
  8. Urinary tract infection
  9. Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
  10. Burning sensation

60+:

  1. Agitation (state of anxiety or nervous excitement)
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Tremor (trembling or shaking movements in one or more parts of your body)
  4. Meningitis bacterial (bacterial inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  5. Pocket erosion

What are the existing conditions these people have? *

  1. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 12 people, 92.31%
  2. Pain: 2 people, 15.38%
  3. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 15.38%
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 7.69%
  5. Paraparesis (partial paralysis of the lower limbs): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Simvastatin and Gablofen?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Simvastatin and Gablofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Simvastatin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gablofen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Simvastatin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gablofen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on simvastatin and baclofen (the active ingredients of Simvastatin and Gablofen, respectively), and Simvastatin and Gablofen (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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