Simvastatin and Maxolon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Maxolon (metoclopramide hydrochloride). Common drug interactions include malignant neoplasm progression among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Maxolon. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Maxolon?

Maxolon has active ingredients of metoclopramide hydrochloride. It is often used in nausea. eHealthMe is studying from 1,977 Maxolon users. Check the latest studies of Maxolon.

On Aug, 06, 2026

66 people who take Simvastatin and Maxolon together, and have interactions are studied.

Simvastatin and Maxolon drug interactions.

What are the common drug interactions of Simvastatin and Maxolon, by gender? *:

female:

Malignant neoplasm progression (cancer tumour came back)
Neutropenia (an abnormally low number of neutrophils)
Renal failure acute (rapid kidney dysfunction)
Renal failure chronic (long lasting kidney dysfunction)
Skin discolouration (change of skin colour)
Thrombocytopenia (decrease of platelets in blood)
Metastases to lung (cancer spreads to lung)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal pain upper
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)

male:

Dehydration (dryness resulting from the removal of water)
Diarrhoea
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Fall
Neutropenia (an abnormally low number of neutrophils)
Pulmonary haemorrhage (acute bleeding from the lung)
Fatigue (feeling of tiredness)
Narcolepsy (brain's inability to regulate sleep-wake cycles normally)
Cardiac disorder
Chest pain

What are the common drug interactions of Simvastatin and Maxolon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Death

40-49:

Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Migraine (headache)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

50-59:

Thrombocytopenia (decrease of platelets in blood)
Upper gastrointestinal haemorrhage (upper gastrointestinal bleeding)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematemesis (vomiting of blood)
Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)

60+:

Dehydration (dryness resulting from the removal of water)
Renal impairment (severely reduced kidney function)
Neutropenia (an abnormally low number of neutrophils)
Malaise (a feeling of general discomfort or uneasiness)
Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Asthenia (weakness)
Atrioventricular block first degree (heart block first degree)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Decreased appetite

What are the existing conditions these people have? *

High Blood Pressure: 13 people, 19.70%
Nausea And Vomiting: 10 people, 15.15%
Diabetes: 10 people, 15.15%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 10.61%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 10.61%
Constipation: 7 people, 10.61%
Insomnia (sleeplessness): 6 people, 9.09%
Indigestion: 6 people, 9.09%
Flatulence (flatus expelled through the anus): 6 people, 9.09%
Dyspnea (difficult or laboured breathing): 6 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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