Simvastatin and Mebendazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Mebendazole (mebendazole). Common drug interactions include insomnia among females and pulmonary embolism among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Mebendazole. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

What is Mebendazole?

Mebendazole has active ingredients of mebendazole. It is often used in pinworms. eHealthMe is studying from 481 Mebendazole users. Check the latest studies of Mebendazole.

On Jul, 10, 2026

12 people who take Simvastatin and Mebendazole together, and have interactions are studied.

Simvastatin and Mebendazole drug interactions.

What are the common drug interactions of Simvastatin and Mebendazole, by gender? *:

female:

Insomnia (sleeplessness)
Muscle spasms (muscle contraction)
Muscle twitching
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Tremor (trembling or shaking movements in one or more parts of your body)
Tooth loss
Agitation (state of anxiety or nervous excitement)
Apathy
Apnoea (suspension of external breathing)

male:

Pulmonary embolism (blockage of the main artery of the lung)
Angioedema (rapid swelling of the dermis)
Drug ineffective

What are the common drug interactions of Simvastatin and Mebendazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Drug ineffective
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

50-59:

Chest discomfort
Cardiovascular disorder (heart diseases)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Dyspnoea (difficult or laboured respiration)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Muscle spasms (muscle contraction)
Muscle twitching
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

60+:

Pulmonary embolism (blockage of the main artery of the lung)
Chronic kidney disease
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Renal disorder (kidney disease)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 41.67%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 41.67%
Depression: 3 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
Pain: 2 people, 16.67%
Bleeding Disorders: 2 people, 16.67%
Gastric Ulcer (stomach ulcer): 2 people, 16.67%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 16.67%
Oedema (fluid collection in tissue): 2 people, 16.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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