Simvastatin and Nubain drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Nubain (nalbuphine hydrochloride). Common drug interactions include chronic kidney disease among females and acute myocardial infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Nubain. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,969 Simvastatin users. Check the latest studies of Simvastatin.

What is Nubain?

Nubain has active ingredients of nalbuphine hydrochloride. It is often used in pain. eHealthMe is studying from 1,749 Nubain users. Check the latest studies of Nubain.

On Jul, 09, 2026

11 people who take Simvastatin and Nubain together, and have interactions are studied.

Simvastatin and Nubain drug interactions.

What are the common drug interactions of Simvastatin and Nubain, by gender? *:

female:

Chronic kidney disease
Drug hypersensitivity
Renal failure (kidney dysfunction)
Nephrogenic anaemia (anaemia due to kidney disease)
Pulmonary embolism (blockage of the main artery of the lung)

male:

Acute myocardial infarction (acute heart attack)
Areflexia (absence of a reflex)
Depression
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic retinal oedema (excessive build-up of fluid in the retina due to diabetes)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Dyspnoea (difficult or laboured respiration)
Emotional disorder
Exercise tolerance decreased

What are the common drug interactions of Simvastatin and Nubain, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)

50-59:

Drug hypersensitivity

60+:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Cataract (clouding of the lens inside the eye)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest discomfort
Chorea (abnormal involuntary movement disorder)
Depression
Diabetes mellitus inadequate control
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Diabetic retinal oedema (excessive build-up of fluid in the retina due to diabetes)

What are the existing conditions these people have? *

High Blood Pressure: 4 people, 36.36%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 36.36%
Infection: 2 people, 18.18%
Asthma: 2 people, 18.18%
Blood Pressure Abnormal: 2 people, 18.18%
Cardiac Disorder: 2 people, 18.18%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 18.18%
Diabetes: 2 people, 18.18%
Dyspnea (difficult or laboured breathing): 2 people, 18.18%
Fever: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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