Simvastatin and Velphoro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Simvastatin (simvastatin) and Velphoro (sucroferric oxyhydroxide). Common drug interactions include chronic kidney disease among females and depression among males.

The phase IV clinical study analyzes what interactions people have when they take Simvastatin and Velphoro. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Simvastatin?

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. eHealthMe is studying from 256,970 Simvastatin users. Check the latest studies of Simvastatin.

What is Velphoro?

Velphoro has active ingredients of sucroferric oxyhydroxide. eHealthMe is studying from 2,749 Velphoro users. Check the latest studies of Velphoro.

On Aug, 11, 2026

30 people who take Simvastatin and Velphoro together, and have interactions are studied.

Simvastatin and Velphoro drug interactions.

What are the common drug interactions of Simvastatin and Velphoro, by gender? *:

female:

Chronic kidney disease
Death
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Diarrhoea
Pruritus (severe itching of the skin)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Haematemesis (vomiting of blood)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypotension (abnormally low blood pressure)

male:

Depression
Renal failure (kidney dysfunction)
Abdominal distension
Abdominal pain
Arteriosclerosis (thickening and hardening of arteries)
Candida sepsis (candida in blood stream)
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Contusion (a type of hematoma of tissue in which capillaries)
Cough

What are the common drug interactions of Simvastatin and Velphoro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Cardiac failure congestive
Cellulitis (infection under the skin)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Pneumonia
Renal failure (kidney dysfunction)

30-39:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Tooth discolouration (a change in colour of teeth)

40-49:

Cardiac failure congestive
Chronic kidney disease
Depression
Intestinal obstruction
Renal failure (kidney dysfunction)
Renal haemangioma (kidney tumour filled with blood)
Renal injury (kidney injury)

50-59:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Depression
Renal injury (kidney injury)
Secondary hyperthyroidism
Post-traumatic stress disorder
Abdominal distension
Arteriosclerosis (thickening and hardening of arteries)
Candida sepsis (candida in blood stream)

60+:

Death
Diarrhoea
Melaena (the passage of black, tarry stools)
Abdominal pain
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal tubular necrosis (death of kidney tubules)
Thrombosis (formation of a blood clot inside a blood vessel)
Pruritus (severe itching of the skin)
Chronic kidney disease

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 33.33%
High Blood Pressure: 9 people, 30.00%
Pain: 9 people, 30.00%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 5 people, 16.67%
Fluid Retention (an abnormal accumulation of fluid in the blood): 5 people, 16.67%
Bacterial Infection: 4 people, 13.33%
Asthma: 4 people, 13.33%
Inflammation: 4 people, 13.33%
Stress And Anxiety: 4 people, 13.33%
Infection: 3 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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