Singulair and Gemzar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Singulair (montelukast sodium) and Gemzar (gemcitabine hydrochloride). Common drug interactions include hypokalaemia among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Singulair and Gemzar. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

What is Gemzar?

Gemzar has active ingredients of gemcitabine hydrochloride. It is often used in pancreatic carcinoma. eHealthMe is studying from 20,315 Gemzar users. Check the latest studies of Gemzar.



On Jul, 26, 2026

53 people who take Singulair and Gemzar together, and have interactions are studied.

Singulair and Gemzar drug interactions.

What are the common drug interactions of Singulair and Gemzar, by gender? *:

female:

  1. Hypokalaemia (low potassium)
  2. Interstitial lung disease
  3. Metastatic neoplasm (spreadable cancer tumour)
  4. Neoplasm malignant (cancer tumour)
  5. Nausea (feeling of having an urge to vomit)
  6. Arthralgia (joint pain)
  7. Asthenia (weakness)
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Chest pain
  10. Cholecystitis (infection of gallbladder)

male:

  1. Anaemia (lack of blood)
  2. Disease progression
  3. Bone disorder
  4. Breath odour
  5. Breath sounds
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Cardiac arrest
  8. Cataract (clouding of the lens inside the eye)
  9. Cerebral atrophy (decrement in size of brain)
  10. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)

What are the common drug interactions of Singulair and Gemzar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Pain
  2. Abdominal pain
  3. Anxiety
  4. Fatigue (feeling of tiredness)
  5. Metastases to liver (cancer spreads to liver)
  6. Metastases to lung (cancer spreads to lung)
  7. Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
  8. Anaemia (lack of blood)
  9. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  10. Atelectasis (partial or complete collapse of the lung)

50-59:

  1. Exostosis (formation of new bone on the surface of a bone)
  2. Osteomyelitis (infection of bone)
  3. Anaemia (lack of blood)
  4. Breath odour
  5. Arthralgia (joint pain)
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  8. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs)
  9. Metastatic neoplasm (spreadable cancer tumour)
  10. Osteoarthritis (a joint disease caused by cartilage loss in a joint)

60+:

  1. Anaemia (lack of blood)
  2. Pyrexia (fever)
  3. Arthralgia (joint pain)
  4. Chest discomfort
  5. Fatigue (feeling of tiredness)
  6. Gestational diabetes (diabetes in pregnancy)
  7. Muscular weakness (muscle weakness)
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  9. Vaginal haemorrhage (vaginal bleeding)
  10. Vomiting

What are the existing conditions these people have? *

  1. Pain: 12 people, 22.64%
  2. Metastases To Bone (cancer spreads to bone): 9 people, 16.98%
  3. Breast Cancer: 7 people, 13.21%
  4. Nausea (feeling of having an urge to vomit): 5 people, 9.43%
  5. Lung Cancer - Non-Small Cell (lung cancer): 5 people, 9.43%
  6. Ovarian Cancer (cancer of ovary): 4 people, 7.55%
  7. Migraine (headache): 4 people, 7.55%
  8. Breast Cancer Female: 4 people, 7.55%
  9. Dyspnea (difficult or laboured breathing): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Singulair and Gemzar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Singulair:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gemzar:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Singulair and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gemzar and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on montelukast sodium and gemcitabine hydrochloride (the active ingredients of Singulair and Gemzar, respectively), and Singulair and Gemzar (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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