Sitagliptin phosphate and Ranitidine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sitagliptin phosphate (sitagliptin phosphate) and Ranitidine (ranitidine). Common drug interactions include toxic epidermal necrolysis among females and deep vein thrombosis among males.

The phase IV clinical study analyzes what interactions people have when they take Sitagliptin phosphate and Ranitidine. It is created by eHealthMe based on reports of 41 people who take the same drugs from the FDA, and is updated regularly.

What is Sitagliptin phosphate?

Sitagliptin phosphate has active ingredients of sitagliptin phosphate. eHealthMe is studying from 3,787 Sitagliptin phosphate users. Check the latest studies of Sitagliptin phosphate.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

On Jul, 06, 2026

41 people who take Sitagliptin phosphate and Ranitidine together, and have interactions are studied.

Sitagliptin phosphate and Ranitidine drug interactions.

What are the common drug interactions of Sitagliptin Phosphate and Ranitidine, by gender? *:

female:

Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Type 2 diabetes mellitus
Upper respiratory tract infection
Urticaria (rash of round, red welts on the skin that itch intensely)
Weight decreased
Wheezing (a high-pitched whistling sound made while you breath)
Accidental exposure
Accidental needle stick
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

male:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures)
Erythema (redness of the skin)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Haemorrhagic anaemia (anaemia due to excessive bleeding)
Hot flush (sudden feelings of heat)
Hypersensitivity
Hypotension (abnormally low blood pressure)
Interstitial lung disease

What are the common drug interactions of Sitagliptin Phosphate and Ranitidine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hot flush (sudden feelings of heat)
Pruritus (severe itching of the skin)
Swelling face

40-49:

Hypoaesthesia (reduced sense of touch or sensation)
Hypochromic anaemia (hypochromic anaemia is a generic term for any type of anaemia in which the red blood cells (erythrocytes) are paler than normal)
Iron deficiency anaemia
Muscle spasms (muscle contraction)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasal dryness (dry nose)
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Obesity (having too much body fat)
Pain

50-59:

Anaemia (lack of blood)
Diarrhoea
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Abdominal pain
Anuria (failure of the kidneys to produce urine)
Cerebral haemorrhage (bleeding within the brain)
Febrile neutropenia (fever with reduced white blood cells)
Malaise (a feeling of general discomfort or uneasiness)
Pneumonia
Respiratory failure (inadequate gas exchange by the respiratory system)

60+:

Hypertension (high blood pressure)
Contusion (a type of hematoma of tissue in which capillaries)
Exercise tolerance decreased
Mobility decreased (ability to move is reduced)
Oedema peripheral (superficial swelling)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Lacunar infarction (a type of stroke)
Renal failure acute (rapid kidney dysfunction)
Subdural haematoma (blood collects between the skull and the surface of the brain)

What are the existing conditions these people have? *

Diabetes: 13 people, 31.71%
High Blood Pressure: 11 people, 26.83%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 9 people, 21.95%
Pain: 9 people, 21.95%
Indigestion: 7 people, 17.07%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 14.63%
Psoriasis (immune-mediated disease that affects the skin): 6 people, 14.63%
Osteoporosis (bones weak and more likely to break): 6 people, 14.63%
Oedema Peripheral (superficial swelling): 6 people, 14.63%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 14.63%

* Approximation only. Some reports may have incomplete information.

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