Slow-k and Flonase drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Slow-k (potassium chloride) and Flonase (fluticasone propionate). Common drug interactions include irritable bowel syndrome among females and back pain among males.
The phase IV clinical study analyzes what interactions people have when they take Slow-k and Flonase. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.
What is Slow-k?
Slow-k has active ingredients of potassium chloride. It is often used in hypokalemia. eHealthMe is studying from 3,683 Slow-k users. Check the latest studies of Slow-k.
What is Flonase?
Flonase has active ingredients of fluticasone propionate. It is often used in allergies. eHealthMe is studying from 75,441 Flonase users. Check the latest studies of Flonase.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
24 people who take Slow-k and Flonase together, and have interactions are studied.

What are the common drug interactions of Slow-K and Flonase, by gender? *:
female:
- Irritable bowel syndrome
- Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
- Neurogenic bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion)
- Oesophageal disorder (disease of oesophagus)
- Pulmonary congestion (congestion in the lungs)
- Pulmonary granuloma (tiny lump of inflamed tissue in the lungs)
- Pulmonary haemorrhage (acute bleeding from the lung)
- Pyrexia (fever)
- Renal failure (kidney dysfunction)
- Renal failure acute (rapid kidney dysfunction)
male:
- Back pain
- Blood pressure increased
- Abdominal distension
- Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals)
- Asthenia (weakness)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Decreased appetite
- Dehydration (dryness resulting from the removal of water)
What are the common drug interactions of Slow-K and Flonase, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Epistaxis (bleed from the nose)
40-49:
n/a
50-59:
- Alopecia (absence of hair from areas of the body)
- Hair disorder
60+:
- Blood pressure increased
- Agitation (state of anxiety or nervous excitement)
- Rib fracture
- Vasculitis (inflammation of a blood vessel or blood vessels)
- Arthralgia (joint pain)
- Erythema (redness of the skin)
- Feeling hot
- Oxygen saturation decreased
- Pruritus (severe itching of the skin)
- Blood pressure systolic increased
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 37.50%
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 4 people, 16.67%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 16.67%
- Swelling: 2 people, 8.33%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 2 people, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Slow-k and Flonase?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Slow-k and Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Slow-k:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flonase:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Slow-k and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flonase and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on potassium chloride and fluticasone propionate (the active ingredients of Slow-k and Flonase, respectively), and Slow-k and Flonase (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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