Solu-cortef and Ritalin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-cortef (hydrocortisone sodium succinate) and Ritalin (methylphenidate hydrochloride). Common drug interactions include malnutrition among females and hypothyroidism among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-cortef and Ritalin. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-cortef?

Solu-cortef has active ingredients of hydrocortisone sodium succinate. eHealthMe is studying from 7,983 Solu-cortef users. Check the latest studies of Solu-cortef.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

On Jul, 20, 2026

17 people who take Solu-cortef and Ritalin together, and have interactions are studied.

Solu-cortef and Ritalin drug interactions.

What are the common drug interactions of Solu-Cortef and Ritalin, by gender? *:

female:

Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Myalgia (muscle pain)
Neck pain
Necrosis (the death of body tissue)
Neoplasm progression (growth of tumour)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pharyngeal erythema (pharyngeal redness)
Pharyngeal inflammation
Pleural disorder

male:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Haematocrit decreased
Haemoglobin decreased
Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
Herpes zoster
Hypersensitivity
Hypotension (abnormally low blood pressure)
Multi-organ failure (multisystem organ failure)
Necrosis (the death of body tissue)

What are the common drug interactions of Solu-Cortef and Ritalin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Vascular rupture
Vein disorder
Weight decreased
Weight increased
Body temperature decreased
Respiratory rate increased (excess breathing rate/min)
Infusion related reaction
Injection site pruritus (severe itching at injection site)
Adverse reaction
Lymphadenitis (inflammation or enlargement of a lymph node)

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Asthenia (weakness)
B-lymphocyte count decreased
Blood pressure decreased
Dehydration (dryness resulting from the removal of water)
Dysphagia (a condition in which swallowing is difficult or painful)
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Erythema (redness of the skin)
Fall

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
Herpes zoster
Hypersensitivity
Hypotension (abnormally low blood pressure)
Multi-organ failure (multisystem organ failure)
Necrosis (the death of body tissue)
Pleural effusion (water on the lungs)
Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

Stress And Anxiety: 8 people, 47.06%
Depression: 8 people, 47.06%
Juvenile Rheumatoid Arthritis (joint inflammation in children due to systemic disease): 6 people, 35.29%
Polyarthritis (arthritis which involves 5 or more joints simultaneously): 5 people, 29.41%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 23.53%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 3 people, 17.65%
Insomnia (sleeplessness): 2 people, 11.76%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 11.76%
Depressed Level Of Consciousness: 2 people, 11.76%
High Blood Pressure: 2 people, 11.76%

* Approximation only. Some reports may have incomplete information.

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