Solu-medrol and Para drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Solu-medrol (methylprednisolone sodium succinate) and Para (para - aminobenzoic acid (paba)). Common drug interactions include infusion related reaction among females and colitis ulcerative among males.

The phase IV clinical study analyzes what interactions people have when they take Solu-medrol and Para. It is created by eHealthMe based on reports of 46 people who take the same drugs from the FDA, and is updated regularly.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

What is Para?

Para has active ingredients of para - aminobenzoic acid (paba). eHealthMe is studying from 2,194 Para users. Check the latest studies of Para.

On Jul, 21, 2026

46 people who take Solu-medrol and Para together, and have interactions are studied.

What are the common drug interactions of Solu-Medrol and Para, by gender? *:

female:

Infusion related reaction
Oral candidiasis (fungal infection of mouth)
Colitis ulcerative (inflammation of colon with ulcer)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Rectal haemorrhage (bleeding from anus)
Frequent bowel movements
Colitis (inflammation of colon)
Constipation
Drug ineffective

male:

Colitis ulcerative (inflammation of colon with ulcer)
Drug ineffective
Frequent bowel movements
Interstitial lung disease
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the common drug interactions of Solu-Medrol and Para, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anaemia (lack of blood)
Colitis ulcerative (inflammation of colon with ulcer)
Fatigue (feeling of tiredness)
Hypersomnia (excessive daytime sleepiness (eds))
Iron deficiency
Malaise (a feeling of general discomfort or uneasiness)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Nasopharyngitis (inflammation of the nasopharynx)
Sinusitis (inflammation of sinus)
Chest pain

30-39:

Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones)
Blindness unilateral
Bradycardia (abnormally slow heart action)
C-reactive protein increased
Diplopia (double vision)
Endocrine ophthalmopathy (increased water content of retroocular orbital tissues; associated with thyroid disease, usually hyperthyroidism)
Fatigue (feeling of tiredness)
Feeling hot
Fungal infection
Headache (pain in head)

40-49:

Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
Infusion related reaction
Irritable bowel syndrome
Pyrexia (fever)
Folliculitis (infection of hair root)
Gastrointestinal disorder (functional problems of gastrointestinal tract)
Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
Infection
Lower respiratory tract infection
Pericarditis (inflammation of the pericardium)

50-59:

Joint swelling
Knee arthroplasty
Laryngitis (inflammation of the larynx)
Live birth
Liver injury
Lung disorder (lung disease)
Lupus vulgaris (a chronic inflammatory autoimmune disorder that may caused by the mycobacterium tuberculosis)
Lupus-like syndrome (a disease symptom matches with lupus an immune disease)
Malaise (a feeling of general discomfort or uneasiness)
Maternal exposure during pregnancy (use of substance during pregnancy)

60+:

Headache (pain in head)
Oral candidiasis (fungal infection of mouth)
Female genital tract fistula (passage in genital tract of female)
Frequent bowel movements
Haematochezia (passage of stools containing blood)
Infusion related reaction
Macular degeneration (painless eye condition that leads to the gradual loss of central vision)
Malaise (a feeling of general discomfort or uneasiness)
Nausea (feeling of having an urge to vomit)
Pain

What are the existing conditions these people have? *

Fever: 19 people, 41.30%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 36.96%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 17 people, 36.96%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 15 people, 32.61%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 14 people, 30.43%
Colitis (inflammation of colon): 14 people, 30.43%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 13 people, 28.26%
Inflammation: 12 people, 26.09%
Pain: 12 people, 26.09%
Pemphigus (any of several acute or chronic skin diseases characterized by groups of itching blisters): 12 people, 26.09%

* Approximation only. Some reports may have incomplete information.

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