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Sonata and Arimidex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sonata (zaleplon) and Arimidex (anastrozole). Common drug interactions include bone disorder among females.

The phase IV clinical study analyzes what interactions people have when they take Sonata and Arimidex. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.

What is Arimidex?

Arimidex has active ingredients of anastrozole. It is often used in breast cancer. eHealthMe is studying from 22,642 Arimidex users. Check the latest studies of Arimidex.

On Jul, 15, 2026

25 people who take Sonata and Arimidex together, and have interactions are studied.

Sonata and Arimidex drug interactions.

What are the common drug interactions of Sonata and Arimidex, by gender? *:

female:

  1. Bone disorder
  2. Pain in jaw
  3. Chest wall mass
  4. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
  5. Decreased appetite
  6. Deformity (disfigurement)
  7. Diarrhoea
  8. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  9. Dizziness
  10. Dry mouth

male:

n/a

What are the common drug interactions of Sonata and Arimidex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Decreased appetite
  2. Deformity (disfigurement)
  3. Diarrhoea
  4. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  5. Dizziness
  6. Dry mouth
  7. Dyspepsia (indigestion)
  8. Dyspnoea (difficult or laboured respiration)
  9. Early satiety (feeling full before completing a normal sized meal)
  10. Emotional distress

60+:

  1. Bone disorder
  2. Bacterial infection
  3. Gingivitis (inflammation of gums)
  4. Glossodynia (a burning or painful sensation in the tongue)
  5. Impaired healing
  6. Pruritus (severe itching of the skin)
  7. Soft tissue infection
  8. Anaemia (lack of blood)
  9. Cough
  10. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 6 people, 24.00%
  2. Osteoporosis (bones weak and more likely to break): 4 people, 16.00%
  3. Multiple Myeloma (cancer of the plasma cells): 4 people, 16.00%
  4. Wheezing (a high-pitched whistling sound made while you breath): 3 people, 12.00%
  5. Weight Increased: 3 people, 12.00%
  6. Type 2 Diabetes: 3 people, 12.00%
  7. Sleep Disorder: 3 people, 12.00%
  8. Oedema (fluid collection in tissue): 3 people, 12.00%
  9. Diabetes: 3 people, 12.00%
  10. Breast Cancer Metastatic: 3 people, 12.00%

* Approximation only. Some reports may have incomplete information.

Do you take Sonata and Arimidex?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sonata and Arimidex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sonata:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Arimidex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sonata and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Arimidex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on zaleplon and anastrozole (the active ingredients of Sonata and Arimidex, respectively), and Sonata and Arimidex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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