Sonata and Nystatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sonata (zaleplon) and Nystatin (nystatin). Common drug interactions include neuralgia among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Sonata and Nystatin. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Sonata?

Sonata has active ingredients of zaleplon. It is often used in insomnia. eHealthMe is studying from 3,330 Sonata users. Check the latest studies of Sonata.

What is Nystatin?

Nystatin has active ingredients of nystatin. It is often used in thrush. eHealthMe is studying from 33,567 Nystatin users. Check the latest studies of Nystatin.

On Jul, 15, 2026

67 people who take Sonata and Nystatin together, and have interactions are studied.

What are the common drug interactions of Sonata and Nystatin, by gender? *:

female:

Neuralgia (pain in one or more nerves)
Neuritis (inflammation of nerve)
Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
Osteonecrosis of jaw (death of bone of jaw)
Pain in jaw
Palpitations (feelings or sensations that your heart is pounding or racing)
Proteinuria (presence of protein in the urine)
Pulmonary oedema (fluid accumulation in the lungs)
Pyrexia (fever)
Pyuria (a condition of urine containing pus)

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Chest pain
Cough
Disease recurrence
Dizziness
Drug hypersensitivity
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Flushing (the warm, red condition of human skin)

What are the common drug interactions of Sonata and Nystatin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Oedema peripheral (superficial swelling)
Anxiety
Cellulitis (infection under the skin)
Depression
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug dependence
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)

50-59:

Urinary tract infection
Abdominal pain
Acquired oesophageal web (structural abnormalities in the oesophagus)
Anxiety
Bone disorder
Breast cancer recurrent
Cardiac failure congestive
Chest wall mass
Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
Decreased appetite

60+:

Anxiety
Decreased appetite
Confusional state
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Memory impairment
Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal pain
Altered state of consciousness (altered state of mind)
Coronary artery bypass

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 13 people, 19.40%
Pain: 9 people, 13.43%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 9 people, 13.43%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 9 people, 13.43%
Breast Cancer: 9 people, 13.43%
Sleep Disorder: 7 people, 10.45%
Osteoporosis (bones weak and more likely to break): 7 people, 10.45%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 7.46%
Multiple Myeloma (cancer of the plasma cells): 4 people, 5.97%
Metastases To Bone (cancer spreads to bone): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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