Spironolactone and Visicol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Spironolactone (spironolactone) and Visicol (sodium phosphate, dibasic, anhydrous; sodium phosphate, monobasic, monohydrate). Common drug interactions include hypoaesthesia among females and acute phosphate nephropathy among males.

The phase IV clinical study analyzes what interactions people have when they take Spironolactone and Visicol. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

What is Visicol?

Visicol has active ingredients of sodium phosphate, dibasic, anhydrous; sodium phosphate, monobasic, monohydrate. eHealthMe is studying from 471 Visicol users. Check the latest studies of Visicol.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 23, 2026

12 people who take Spironolactone and Visicol together, and have interactions are studied.

Spironolactone and Visicol drug interactions.

What are the common drug interactions of Spironolactone and Visicol, by gender? *:

female:

  1. Hypoaesthesia (reduced sense of touch or sensation)
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Blood pressure decreased
  4. Renal failure acute (rapid kidney dysfunction)
  5. Renal impairment (severely reduced kidney function)
  6. Blood calcium decreased
  7. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  8. Memory impairment
  9. Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals)
  10. Chronic kidney disease

male:

  1. Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals)
  2. Dyslalia (inability to articulate comprehensible speech)
  3. Chest pain
  4. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
  5. Hypoaesthesia (reduced sense of touch or sensation)
  6. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  7. Renal impairment (severely reduced kidney function)
  8. Respiratory paralysis (respiratory failure)
  9. Tetany (involuntary contraction of muscles)
  10. Urine output decreased

What are the common drug interactions of Spironolactone and Visicol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals)
  2. Dyslalia (inability to articulate comprehensible speech)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  5. Renal impairment (severely reduced kidney function)
  6. Respiratory paralysis (respiratory failure)
  7. Tetany (involuntary contraction of muscles)
  8. Urine output decreased
  9. Blood creatinine increased
  10. Blood urea increased

40-49:

n/a

50-59:

  1. Renal impairment (severely reduced kidney function)
  2. Acute phosphate nephropathy (sudden damage to the kidneys caused by the formation of phosphate crystals)
  3. Chronic kidney disease
  4. Dyslalia (inability to articulate comprehensible speech)
  5. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  8. Renal failure (kidney dysfunction)
  9. Respiratory paralysis (respiratory failure)
  10. Tetany (involuntary contraction of muscles)

60+:

  1. Malaise (a feeling of general discomfort or uneasiness)
  2. Blood pressure decreased
  3. Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
  4. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  5. Nephropathy (damage to or disease of a kidney)
  6. Post procedural complication
  7. Rash
  8. Hypoaesthesia (reduced sense of touch or sensation)
  9. Renal failure acute (rapid kidney dysfunction)
  10. Blood calcium decreased

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 25.00%
  2. High Blood Pressure: 3 people, 25.00%
  3. High Blood Cholesterol: 3 people, 25.00%
  4. Hypersensitivity: 2 people, 16.67%
  5. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 16.67%
  6. Gastric Ph Decreased: 2 people, 16.67%
  7. Bone Disorder: 2 people, 16.67%
  8. Asthma: 2 people, 16.67%
  9. Arthropathy: 2 people, 16.67%
  10. Pain In Extremity: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Spironolactone and Visicol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Spironolactone and Visicol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Spironolactone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Visicol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Spironolactone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Visicol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on spironolactone and sodium phosphate, dibasic, anhydrous; sodium phosphate, monobasic, monohydrate (the active ingredients of Spironolactone and Visicol, respectively), and Spironolactone and Visicol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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