Sprycel and Hctz drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sprycel (dasatinib) and Hctz (hydrochlorothiazide). Common drug interactions include normal newborn among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Sprycel and Hctz. It is created by eHealthMe based on reports of 67 people who take the same drugs from the FDA, and is updated regularly.

What is Sprycel?

Sprycel has active ingredients of dasatinib. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 29,788 Sprycel users. Check the latest studies of Sprycel.

What is Hctz?

Hctz has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 24,823 Hctz users. Check the latest studies of Hctz.

On Jul, 09, 2026

67 people who take Sprycel and Hctz together, and have interactions are studied.

What are the common drug interactions of Sprycel and Hctz, by gender? *:

female:

Normal newborn
Oedema peripheral (superficial swelling)
Oropharyngeal pain
Peripheral swelling
Pleural effusion (water on the lungs)
Pneumonia
Productive cough
Pulmonary oedema (fluid accumulation in the lungs)
Renal failure acute (rapid kidney dysfunction)
Respiratory failure (inadequate gas exchange by the respiratory system)

male:

Pneumonia
Fatigue (feeling of tiredness)
Night sweats (sweating in night)
Pericardial effusion (fluid around the heart)
Abdominal distension
Abdominal pain
Acne (skin problems that cause pimples)
Alopecia (absence of hair from areas of the body)
Blood lactate dehydrogenase increased
Cardiac arrest

What are the common drug interactions of Sprycel and Hctz, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal discomfort
Diarrhoea
Dry skin
Eye swelling
Fatigue (feeling of tiredness)
Headache (pain in head)
Memory impairment
Nausea (feeling of having an urge to vomit)
Pain
Skin disorder (skin disease)

50-59:

Nausea (feeling of having an urge to vomit)
Adverse event
Constipation
Diarrhoea
Rash
Abdominal discomfort
Gastric disorder (disease of stomach)
Decreased appetite
Fatigue (feeling of tiredness)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

Cough
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Photosensitivity reaction
Pneumonia
Rash
Thrombocytopenia (decrease of platelets in blood)
Tonsillitis (inflammation of tonsil)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 49 people, 73.13%
Leukaemia (blood or bone marrow cancer): 4 people, 5.97%

* Approximation only. Some reports may have incomplete information.

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