Stivarga and Acetaminophen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Stivarga (regorafenib) and Acetaminophen (acetaminophen). Common drug interactions include asthenia among females and disease progression among males.

The phase IV clinical study analyzes what interactions people have when they take Stivarga and Acetaminophen. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Stivarga?

Stivarga has active ingredients of regorafenib. eHealthMe is studying from 9,539 Stivarga users. Check the latest studies of Stivarga.

What is Acetaminophen?

Acetaminophen has active ingredients of acetaminophen. It is often used in pain. eHealthMe is studying from 183,077 Acetaminophen users. Check the latest studies of Acetaminophen.

On Aug, 09, 2026

18 people who take Stivarga and Acetaminophen together, and have interactions are studied.

Stivarga and Acetaminophen drug interactions.

What are the common drug interactions of Stivarga and Acetaminophen, by gender? *:

female:

Asthenia (weakness)
Fatigue (feeling of tiredness)
Rash
Dehydration (dryness resulting from the removal of water)
Dizziness
Hypotension (abnormally low blood pressure)
Alopecia (absence of hair from areas of the body)
Arthralgia (joint pain)
Blood calcium decreased
Blood iron decreased

male:

Disease progression
Dehydration (dryness resulting from the removal of water)
Leukopenia (less number of white blood cells in blood)
Oxygen saturation decreased
Pulmonary embolism (blockage of the main artery of the lung)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Vomiting
Nephrolithiasis (calculi in the kidneys)
Neuropathy peripheral (surface nerve damage)
Abdominal pain

What are the common drug interactions of Stivarga and Acetaminophen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Death
Fatigue (feeling of tiredness)
Peripheral swelling
Vision blurred

40-49:

Dehydration (dryness resulting from the removal of water)
Asthenia (weakness)
Dry skin
Encephalopathy (functioning of the brain is affected by some agent or condition)
General physical health deterioration (weak health status)
Intestinal haemorrhage (bleeding from intestine)
Ocular icterus (presence of jaundice seen in the sclera of the eye)
Weight decreased
Disease progression
Oxygen saturation decreased

50-59:

Disease progression

60+:

Diarrhoea
Abdominal pain
Dysphagia (a condition in which swallowing is difficult or painful)
Fatigue (feeling of tiredness)
Oral mucosal blistering (mouth ulcer)
Oropharyngeal blistering (blister of oropharynx)
Skin exfoliation (removal of the oldest dead skin cells)
Stomatitis (inflammation of mucous membrane of mouth)
Tenderness (pain or discomfort when an affected area is touched)
Thermal burn (burn by heat)

What are the existing conditions these people have? *

Colon Cancer: 9 people, 50.00%
Gastrointestinal Stromal Tumor: 4 people, 22.22%
Stress And Anxiety: 3 people, 16.67%
High Blood Pressure: 3 people, 16.67%
Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 11.11%
Fever: 1 person, 5.56%
Affective Disorder (mental disorder): 1 person, 5.56%
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 5.56%
Colon Neoplasm (cancer from uncontrolled cell growth in the colon or rectum): 1 person, 5.56%
Colorectal Cancer Stage Iv (cancer of colon and rectal spreads to liver or lung): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Stivarga and Acetaminophen?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously