Sublocade and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sublocade (buprenorphine) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include fatigue among females and irritability among males.

The phase IV clinical study analyzes what interactions people have when they take Sublocade and Adderall. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Sublocade?

Sublocade has active ingredients of buprenorphine. eHealthMe is studying from 4,530 Sublocade users. Check the latest studies of Sublocade.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,225 Adderall users. Check the latest studies of Adderall.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 23, 2026

17 people who take Sublocade and Adderall together, and have interactions are studied.

Sublocade and Adderall drug interactions.

What are the common drug interactions of Sublocade and Adderall, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Injection site pain
  3. Abdominal pain
  4. Blood lactate dehydrogenase increased
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Drug abuse
  7. Drug dependence
  8. Drug detoxification
  9. Dysphoria (generalized dissatisfaction with life)
  10. Dysuria (painful or difficult urination)

male:

  1. Irritability
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Nausea (feeling of having an urge to vomit)
  4. Aggression
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Sublocade and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Aggression
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Irritability
  4. Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

  1. Dysphoria (generalized dissatisfaction with life)
  2. Headache (pain in head)
  3. Nausea (feeling of having an urge to vomit)
  4. Injection site pain
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

40-49:

  1. Drug dependence
  2. Dysuria (painful or difficult urination)
  3. Nausea (feeling of having an urge to vomit)
  4. Oedema peripheral (superficial swelling)
  5. Vomiting

50-59:

  1. Irritability
  2. Malaise (a feeling of general discomfort or uneasiness)
  3. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

60+:

n/a

What are the existing conditions these people have? *

  1. Drug Dependence: 6 people, 35.29%
  2. Sleep Disorder: 2 people, 11.76%
  3. Polycystic Ovary Disease (cysts in the ovaries that occurs when the follicle stops developing): 2 people, 11.76%
  4. Depression: 2 people, 11.76%
  5. Stress And Anxiety: 1 person, 5.88%
  6. Personality Disorder: 1 person, 5.88%
  7. Pain: 1 person, 5.88%
  8. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 1 person, 5.88%
  9. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 1 person, 5.88%
  10. Drowsiness: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sublocade and Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sublocade:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sublocade and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Sublocade and Adderall, respectively), and Sublocade and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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