Sublocade and Clonazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sublocade (buprenorphine) and Clonazepam (clonazepam). Common drug interactions include drug abuse among females and drug withdrawal syndrome among males.

The phase IV clinical study analyzes what interactions people have when they take Sublocade and Clonazepam. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Sublocade?

Sublocade has active ingredients of buprenorphine. eHealthMe is studying from 4,530 Sublocade users. Check the latest studies of Sublocade.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.



On Jul, 05, 2026

11 people who take Sublocade and Clonazepam together, and have interactions are studied.

Sublocade and Clonazepam drug interactions.

What are the common drug interactions of Sublocade and Clonazepam, by gender? *:

female:

  1. Drug abuse
  2. Decreased appetite
  3. Depression
  4. Injection site pain
  5. Nausea (feeling of having an urge to vomit)
  6. Vomiting

male:

  1. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  2. Blood pressure increased
  3. Injection site reaction
  4. Drug abuse
  5. Euphoric mood (excessively happy but may become angry or irritable)
  6. Nausea (feeling of having an urge to vomit)
  7. Pain
  8. Chest pain
  9. Drug dependence
  10. Fatigue (feeling of tiredness)

What are the common drug interactions of Sublocade and Clonazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Drug abuse
  2. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  3. Euphoric mood (excessively happy but may become angry or irritable)

30-39:

  1. Drug abuse
  2. Decreased appetite
  3. Injection site pain
  4. Nausea (feeling of having an urge to vomit)
  5. Vomiting

40-49:

  1. Blood pressure increased
  2. Chest pain
  3. Drug dependence
  4. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  5. Fatigue (feeling of tiredness)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Memory impairment
  8. Restlessness (not able to rest)
  9. Somnolence (a state of near-sleep, a strong desire for sleep)
  10. Depression

50-59:

  1. Blood pressure increased
  2. Chest pain
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Drug dependence
  5. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  6. Fatigue (feeling of tiredness)
  7. Injection site pain
  8. Injection site reaction
  9. Malaise (a feeling of general discomfort or uneasiness)
  10. Memory impairment

60+:

n/a

What are the existing conditions these people have? *

  1. Drug Dependence: 7 people, 63.64%
  2. Sleep Disorder: 1 person, 9.09%
  3. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 1 person, 9.09%
  4. Migraine (headache): 1 person, 9.09%
  5. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 1 person, 9.09%
  6. Acne (skin problems that cause pimples): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Sublocade and Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Sublocade:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Clonazepam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sublocade and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clonazepam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on buprenorphine and clonazepam (the active ingredients of Sublocade and Clonazepam, respectively), and Sublocade and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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