Suboxone and Astelin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) and Astelin (azelastine hydrochloride). Common drug interactions include fall among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Suboxone and Astelin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Suboxone?

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 31,249 Suboxone users. Check the latest studies of Suboxone.

What is Astelin?

Astelin has active ingredients of azelastine hydrochloride. It is often used in allergies. eHealthMe is studying from 5,538 Astelin users. Check the latest studies of Astelin.

On Jul, 18, 2026

20 people who take Suboxone and Astelin together, and have interactions are studied.

What are the common drug interactions of Suboxone and Astelin, by gender? *:

female:

Fall
Weight decreased
Back injury
Bone disorder
Cholangitis sclerosing (infection and obstruction of bile duct)
Colitis ulcerative (inflammation of colon with ulcer)
Malaise (a feeling of general discomfort or uneasiness)
Peripheral swelling
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Pyrexia (fever)

male:

Chest pain
Cough
Headache (pain in head)
Hospitalisation
Inguinal hernia (hernia in which a loop of intestine enters the inguinal canal; the most common type of hernia in males)
Oropharyngeal pain
Rhinorrhoea (watery mucus discharge from the nose)
Sneezing

What are the common drug interactions of Suboxone and Astelin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

40-49:

n/a

50-59:

n/a

60+:

Weight increased
Influenza
Sedation
Suicidal ideation
Glaucoma (increased fluid pressure in the eye with vision loss)
Peripheral swelling
Chest pain
Cough
Drug hypersensitivity
Headache (pain in head)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 45.00%
Apnea (temporary absence or cessation of breathing): 6 people, 30.00%
Sleep Apnea Syndrome: 4 people, 20.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 20.00%
Drowsiness: 4 people, 20.00%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 10.00%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 2 people, 10.00%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 10.00%
Pain: 1 person, 5.00%
Insomnia (sleeplessness): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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