Suboxone and Escitalopram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Suboxone (buprenorphine hydrochloride; naloxone hydrochloride) and Escitalopram (escitalopram oxalate). Common drug interactions include overdose among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Suboxone and Escitalopram. It is created by eHealthMe based on reports of 99 people who take the same drugs from the FDA, and is updated regularly.

What is Suboxone?

Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. It is often used in opiate withdrawal. eHealthMe is studying from 31,249 Suboxone users. Check the latest studies of Suboxone.

What is Escitalopram?

Escitalopram has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 78,080 Escitalopram users. Check the latest studies of Escitalopram.

On Jul, 08, 2026

99 people who take Suboxone and Escitalopram together, and have interactions are studied.

Suboxone and Escitalopram drug interactions.

What are the common drug interactions of Suboxone and Escitalopram, by gender? *:

female:

Overdose
Rectal haemorrhage (bleeding from anus)
Vomiting
Weight fluctuation
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Chest discomfort
Electrocardiogram qt prolonged
Fear
Hypertension (high blood pressure)
Infection

male:

Nausea (feeling of having an urge to vomit)
Pain
Weight decrease neonatal
Death
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Loss of consciousness
Drug dependence
Oedema peripheral (superficial swelling)
Overdose
Vomiting

What are the common drug interactions of Suboxone and Escitalopram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug ineffective
Acute respiratory distress syndrome
Injection site erythema (redness at injection site)
Injection site extravasation (flow of (blood or lymph) from injection site)
Injection site necrosis (death of body tissue at injection site)
Injection site pain
Oral mucosal exfoliation (removal of mucous membrane of mouth)
Pneumonia
Stomatitis (inflammation of mucous membrane of mouth)

30-39:

Drug dependence
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Asthma
Cardiac failure congestive
Nausea (feeling of having an urge to vomit)
Blood pressure increased
Chronic kidney disease
Vomiting
Alcohol abuse

40-49:

Diarrhoea
Drug ineffective
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dysgeusia (disorder of the sense of taste)
Malaise (a feeling of general discomfort or uneasiness)
Myalgia (muscle pain)
Cardiac arrest
Chronic kidney disease
Exostosis (formation of new bone on the surface of a bone)
Fall

50-59:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Feeling cold
Fluid retention (an abnormal accumulation of fluid in the blood)
Laziness
Pain
Insomnia (sleeplessness)
Pruritus (severe itching of the skin)
Rash
Rash pruritic (redness with itching)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

60+:

Nausea (feeling of having an urge to vomit)
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Dizziness
Erythema (redness of the skin)
Flatulence (flatus expelled through the anus)
Impaired work ability
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neuropathy peripheral (surface nerve damage)
Oedema peripheral (superficial swelling)
Poor quality sleep

What are the existing conditions these people have? *

Pain: 16 people, 16.16%
Stress And Anxiety: 14 people, 14.14%
Drug Dependence: 11 people, 11.11%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 8 people, 8.08%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 6.06%
High Blood Pressure: 5 people, 5.05%

* Approximation only. Some reports may have incomplete information.

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