Sulfatrim and Seroquel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulfatrim (sulfamethoxazole; trimethoprim) and Seroquel (quetiapine fumarate). Common drug interactions include neuropathy peripheral among females and urinary tract infection among males.

The phase IV clinical study analyzes what interactions people have when they take Sulfatrim and Seroquel. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Sulfatrim?

Sulfatrim has active ingredients of sulfamethoxazole; trimethoprim. eHealthMe is studying from 4,140 Sulfatrim users. Check the latest studies of Sulfatrim.

What is Seroquel?

Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,287 Seroquel users. Check the latest studies of Seroquel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

27 people who take Sulfatrim and Seroquel together, and have interactions are studied.

Sulfatrim and Seroquel drug interactions.

What are the common drug interactions of Sulfatrim and Seroquel, by gender? *:

female:

Neuropathy peripheral (surface nerve damage)
Pain
Polymyalgia rheumatica (pain in many muscles)
Rash
Renal failure (kidney dysfunction)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Skin disorder (skin disease)
Speech disorder
Tendonitis (a condition that causes pain and swelling of tendons)
Thrombosis (formation of a blood clot inside a blood vessel)

male:

Urinary tract infection
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Drug ineffective
Haematuria (presence of blood in urine)
Hypokalaemia (low potassium)
Leukocytosis (increased white blood cells)
Mania (a state of abnormally elevated or irritable mood)
Pain
Productive cough
Burning sensation

What are the common drug interactions of Sulfatrim and Seroquel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Hyperglycaemia (high blood sugar)
Chest pain
Deformity (disfigurement)
Emotional distress
Gynaecomastia (enlargement of the gland tissue of the male breast)
Pain

40-49:

Headache (pain in head)
Abdominal discomfort
Abdominal pain upper
Anaemia (lack of blood)
Arthralgia (joint pain)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Carbohydrate metabolism disorder (inability of carbohydrate metabolism)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diarrhoea
Herpes simplex (herpes simplex is a common viral infection)

50-59:

Drug hypersensitivity
Renal failure (kidney dysfunction)
Blood pressure increased
Cardiac failure congestive
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Oedema peripheral (superficial swelling)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Retinal detachment (a disorder of the eye in which the retina peels away from its underlying layer of support tissue)
Type 2 diabetes mellitus
Chronic kidney disease

60+:

Urinary tract infection
Hallucination (an experience involving the perception of something not present)
Arthralgia (joint pain)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Coma (state of unconsciousness lasting more than six hours)
Contusion (a type of hematoma of tissue in which capillaries)
Dehydration (dryness resulting from the removal of water)
Drug ineffective
Fatigue (feeling of tiredness)
Fluid retention (an abnormal accumulation of fluid in the blood)

What are the existing conditions these people have? *

Depression: 9 people, 33.33%
Stress And Anxiety: 7 people, 25.93%
Sleep Disorder: 6 people, 22.22%
Vasculitis (inflammation of a blood vessel or blood vessels): 4 people, 14.81%
Parkinson's Disease: 3 people, 11.11%
Pain: 3 people, 11.11%
Mania (a state of abnormally elevated or irritable mood): 2 people, 7.41%
Anger: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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