Sulindac and Xanax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Sulindac (sulindac) and Xanax (alprazolam). Common drug interactions include paraesthesia among females and tremor among males.

The phase IV clinical study analyzes what interactions people have when they take Sulindac and Xanax. It is created by eHealthMe based on reports of 57 people who take the same drugs from the FDA, and is updated regularly.

What is Sulindac?

Sulindac has active ingredients of sulindac. It is often used in rheumatoid arthritis. eHealthMe is studying from 3,824 Sulindac users. Check the latest studies of Sulindac.

What is Xanax?

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 135,347 Xanax users. Check the latest studies of Xanax.

On Jul, 16, 2026

57 people who take Sulindac and Xanax together, and have interactions are studied.

What are the common drug interactions of Sulindac and Xanax, by gender? *:

female:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pruritus (severe itching of the skin)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Renal failure acute (rapid kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Rotator cuff syndrome (a spectrum of conditions affecting the rotator cuff tendons of the shoulder)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
Sleep disorder
Tachyarrhythmia (disturbance of the heart rhythm in which the heart rate is abnormally increased)
Type 2 diabetes mellitus

male:

Tremor (trembling or shaking movements in one or more parts of your body)
Aggression
Hypertension (high blood pressure)
Pain in extremity
Type 2 diabetes mellitus
Alcoholism (problems with alcohol)
Asthenia (weakness)
Cardiac failure congestive
Cellulitis (infection under the skin)
Cerebral atrophy (decrement in size of brain)

What are the common drug interactions of Sulindac and Xanax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Decreased appetite
Dizziness
Drug ineffective
Granuloma (a small area of inflammation due to tissue injury)
Haemorrhage (bleeding)
Headache (pain in head)
Nausea (feeling of having an urge to vomit)

20-29:

n/a

30-39:

n/a

40-49:

Suicidal ideation
Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression)
Depression
Drug ineffective
General physical health deterioration (weak health status)
Back pain
Borderline personality disorder
Cervical spinal stenosis (narrowing of the spinal canal in the neck)
Intervertebral disc protrusion (spinal disc protrusion)
Myalgia (muscle pain)

50-59:

Hypertension (high blood pressure)
Incontinence (lack of moderation or self-control)
Joint stiffness
Nausea (feeling of having an urge to vomit)
Osteopenia (a condition where bone mineral density is lower than normal)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur)
Sinusitis (inflammation of sinus)
Skin exfoliation (removal of the oldest dead skin cells)
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

60+:

Diarrhoea
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Abdominal pain
Blood cholesterol increased
Bradycardia (abnormally slow heart action)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac failure
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cellulitis (infection under the skin)
Chronic kidney disease

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 15.79%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 6 people, 10.53%
High Blood Pressure: 5 people, 8.77%
Pain: 4 people, 7.02%
High Blood Cholesterol: 4 people, 7.02%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.02%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 7.02%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 5.26%
Inflammation: 3 people, 5.26%
Cardiac Disorder: 3 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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