Cevimeline and Valtrex drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cevimeline (cevimeline hydrochloride) and Valtrex (valacyclovir hydrochloride). Common drug interactions include urinary tract infection among females and amyotrophic lateral sclerosis among males.
The phase IV clinical study analyzes what interactions people have when they take Cevimeline and Valtrex. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.
What is Cevimeline?
Cevimeline has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,480 Cevimeline users. Check the latest studies of Cevimeline.
What is Valtrex?
Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 39,999 Valtrex users. Check the latest studies of Valtrex.
51 people who take Cevimeline and Valtrex together, and have interactions are studied.

What are the common drug interactions of Cevimeline and Valtrex, by gender? *:
female:
- Urinary tract infection
- Pain in extremity
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
- Poor venous access
- Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
- Vein disorder
- Weight decreased
- Diarrhoea
- Erythema (redness of the skin)
male:
- Amyotrophic lateral sclerosis (nervous system disease that attacks nerve cells called neurons in your brain and spinal cord)
- Ankylosing spondylitis (type of arthritis affecting the spine)
- Therapeutic response unexpected
- Therapeutic response decreased (less preventive response)
- Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
- Drug ineffective
- Eye irritation
- Eye pain
- Legionella infection (a lung infection caused by bacteria of the species legionella)
- Oesophagitis (inflammation of oesophagus)
What are the common drug interactions of Cevimeline and Valtrex, by age (0-1 to 60+)? *:
0-1:
- Urinary tract infection
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Nasal septum deviation (deviated nasal septum)
- Peripheral swelling
- Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
- Swelling face
- Asthma
- Dyspnoea (difficult or laboured respiration)
- Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
- Erythema (redness of the skin)
- Impaired gastric emptying
- Malaise (a feeling of general discomfort or uneasiness)
50-59:
- Pain in extremity
- Pleurisy (inflammation of the pleurae, which causes pain when breathing)
- Poor venous access
- Urinary tract infection
- Vein disorder
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Renal impairment (severely reduced kidney function)
- Pain
- Allergic sinusitis
- Tooth infection
60+:
- Accident at home
- Diarrhoea
- Hallucination (an experience involving the perception of something not present)
- Immunoglobulins decreased
- Nausea (feeling of having an urge to vomit)
- Psychotic disorder
- Renal failure (kidney dysfunction)
- Arthralgia (joint pain)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Vomiting
What are the existing conditions these people have? *
- Immunodeficiency Common Variable: 16 people, 31.37%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 11 people, 21.57%
- Immune System Disorder: 8 people, 15.69%
- Primary Immunodeficiency Syndrome: 5 people, 9.80%
* Approximation only. Some reports may have incomplete information.
Do you take Cevimeline and Valtrex?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cevimeline (1,480 reports)
- Valtrex (39,999 reports)
Browse all drug interactions of Cevimeline and Valtrex:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cevimeline:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Valtrex:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cevimeline and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Valtrex and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cevimeline hydrochloride and valacyclovir hydrochloride (the active ingredients of Cevimeline and Valtrex, respectively), and Cevimeline and Valtrex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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