Suprax and Amoxicillin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Suprax (cefixime) and Amoxicillin (amoxicillin). Common drug interactions include gastrooesophageal reflux disease among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Suprax and Amoxicillin. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Suprax?

Suprax has active ingredients of cefixime. eHealthMe is studying from 965 Suprax users. Check the latest studies of Suprax.

What is Amoxicillin?

Amoxicillin has active ingredients of amoxicillin. It is often used in infection. eHealthMe is studying from 99,235 Amoxicillin users. Check the latest studies of Amoxicillin.



On Jul, 13, 2026

64 people who take Suprax and Amoxicillin together, and have interactions are studied.

Suprax and Amoxicillin drug interactions.

What are the common drug interactions of Suprax and Amoxicillin, by gender? *:

female:

  1. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  2. Melaena (the passage of black, tarry stools)
  3. Otitis externa (external ear infection)
  4. Presbyopia (a condition in which the lens of the eye loses its ability to focus, making it difficult to see objects up close)
  5. Restless legs syndrome (a powerful urge to move your legs)
  6. Schizoaffective disorder (a mental disorder characterized by disordered thought)
  7. Vaginal infection
  8. Back pain
  9. Headache (pain in head)
  10. Insomnia (sleeplessness)

male:

  1. Anxiety
  2. Chronic kidney disease
  3. Dysstasia (difficulty in standing)
  4. Gait disturbance
  5. Hand fracture
  6. Muscle spasms (muscle contraction)
  7. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  8. Nausea (feeling of having an urge to vomit)
  9. Osteoporosis (bones weak and more likely to break)
  10. Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)

What are the common drug interactions of Suprax and Amoxicillin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Pyrexia (fever)
  2. Cough
  3. Insomnia (sleeplessness)
  4. Otitis media (inflammation of the middle ear)
  5. Pneumonia
  6. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
  7. Upper respiratory tract infection
  8. Abdominal pain
  9. Alanine aminotransferase increased
  10. Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)

10-19:

  1. Hyperglycaemia (high blood sugar)
  2. Chronic kidney disease
  3. Peripheral motor neuropathy (muscles in the body become progressively weaker over months to years)
  4. Peripheral sensory neuropathy (damage to one or more of your peripheral nerves)
  5. Abdominal mass (localized enlargement or swelling in the human abdomen)
  6. Acute respiratory failure
  7. Asthenia (weakness)
  8. Back pain
  9. Body height decreased
  10. Breath sounds

20-29:

n/a

30-39:

  1. Abdominal discomfort
  2. Drug hypersensitivity

40-49:

  1. Chronic kidney disease
  2. Renal disorder (kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Abdominal pain
  5. Affect lability (emotional incontinence)
  6. Anxiety
  7. Bradycardia (abnormally slow heart action)
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Chest pain
  10. Constipation

50-59:

  1. Migraine (headache)
  2. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  3. Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
  4. Osteopenia (a condition where bone mineral density is lower than normal)
  5. Osteoporosis (bones weak and more likely to break)
  6. Otitis media acute (rapid inflammation of the middle ear)
  7. Pain
  8. Quality of life decreased
  9. Renal failure (kidney dysfunction)
  10. Stomatitis (inflammation of mucous membrane of mouth)

60+:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Alcohol use
  4. Asthenia (weakness)
  5. Back pain
  6. Blood cholesterol increased
  7. Blood creatinine increased
  8. Blood magnesium decreased
  9. Blood potassium decreased
  10. Blood pressure increased

What are the existing conditions these people have? *

  1. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 31.25%
  2. High Blood Pressure: 13 people, 20.31%
  3. Pain: 12 people, 18.75%
  4. High Blood Cholesterol: 12 people, 18.75%
  5. Depression: 8 people, 12.50%
  6. Asthma: 7 people, 10.94%
  7. Stress And Anxiety: 6 people, 9.38%
  8. Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 9.38%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 6 people, 9.38%
  10. Hyperlipidaemia (presence of excess lipids in the blood): 6 people, 9.38%

* Approximation only. Some reports may have incomplete information.

Do you take Suprax and Amoxicillin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Suprax and Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Suprax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Amoxicillin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Suprax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Amoxicillin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cefixime and amoxicillin (the active ingredients of Suprax and Amoxicillin, respectively), and Suprax and Amoxicillin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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