Sylvant and Acyclovir drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Sylvant (siltuximab) and Acyclovir (acyclovir). Common drug interactions include cytokine release syndrome among females.
The phase IV clinical study analyzes what interactions people have when they take Sylvant and Acyclovir. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.
What is Sylvant?
Sylvant has active ingredients of siltuximab. eHealthMe is studying from 268 Sylvant users. Check the latest studies of Sylvant.
What is Acyclovir?
Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.
32 people who take Sylvant and Acyclovir together, and have interactions are studied.

What are the common drug interactions of Sylvant and Acyclovir, by gender? *:
female:
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
- Disease progression
- Neoplasm progression (growth of tumour)
male:
n/a
What are the common drug interactions of Sylvant and Acyclovir, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
60+:
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Diffuse large b-cell lymphoma (cancer of b cells, a type of white blood cell)
- Disease progression
- Neoplasm progression (growth of tumour)
What are the existing conditions these people have? *
- Cytokine Release Syndrome (immediate complication occurring with the use of anti-t cell antibody infusions): 30 people, 93.75%
- Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 28 people, 87.50%
* Approximation only. Some reports may have incomplete information.
Do you take Sylvant and Acyclovir?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Sylvant and Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Sylvant:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Acyclovir:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Sylvant and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acyclovir and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
- Choi N, Lee JY, Sunwoo JS, Kwon KI, Roh H, Ahn MY, Lee KB, "Hyponatremia during Acyclovir Treatment of Bell’s Palsy", Journal of the Korean Neurological Association, 2017 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on siltuximab and acyclovir (the active ingredients of Sylvant and Acyclovir, respectively), and Sylvant and Acyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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