Symbyax and Celexa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Symbyax (fluoxetine hydrochloride; olanzapine) and Celexa (citalopram hydrobromide). Common drug interactions include pruritus among females and diabetes mellitus among males.

The phase IV clinical study analyzes what interactions people have when they take Symbyax and Celexa. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Symbyax?

Symbyax has active ingredients of fluoxetine hydrochloride; olanzapine. It is often used in depression. eHealthMe is studying from 1,449 Symbyax users. Check the latest studies of Symbyax.

What is Celexa?

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 56,390 Celexa users. Check the latest studies of Celexa.

On Jul, 10, 2026

48 people who take Symbyax and Celexa together, and have interactions are studied.

What are the common drug interactions of Symbyax and Celexa, by gender? *:

female:

Pruritus (severe itching of the skin)
Vaginal haemorrhage (vaginal bleeding)
Vision blurred
Blood creatine phosphokinase increased
Blood urea decreased
Chest discomfort
Hyperventilation
Leukocytosis (increased white blood cells)
Malaise (a feeling of general discomfort or uneasiness)
Vomiting

male:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Cardiac disorder
Hyperhidrosis (abnormally increased sweating)
Infection
Lethargy (tiredness)
Neuropathy peripheral (surface nerve damage)
Pyrexia (fever)
Spinal osteoarthritis (joint cartilage loss in spine)
Upper respiratory tract infection
Urinary tract infection

What are the common drug interactions of Symbyax and Celexa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Blood cholesterol increased
Glycosuria (excretion of glucose into the urine)
Hyperlipidaemia (presence of excess lipids in the blood)
Intervertebral disc protrusion (spinal disc protrusion)
Obesity (having too much body fat)
Type 2 diabetes mellitus
Chest pain
Constipation
Diarrhoea
Epistaxis (bleed from the nose)

30-39:

Weight increased
Blood cholesterol increased
Type 2 diabetes mellitus
Blood triglycerides increased
Headache (pain in head)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Obesity (having too much body fat)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)

40-49:

Blood oestrogen decreased
Chest pain
Diarrhoea
Dizziness
Fatigue (feeling of tiredness)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Vaginal haemorrhage (vaginal bleeding)
Vision blurred
Blood creatine phosphokinase increased
Blood urea decreased

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Cardiac disorder
Dyspnoea (difficult or laboured respiration)
Hypertension (high blood pressure)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Coeliac disease (simple food intolerance)
Diabetic complication
Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
Dizziness
Gastrointestinal disorder (functional problems of gastrointestinal tract)

60+:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Oedema peripheral (superficial swelling)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Influenza
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Blood pressure systolic increased
Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dizziness

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 23 people, 47.92%
Stress And Anxiety: 17 people, 35.42%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 6 people, 12.50%
Restless Leg Syndrome (a powerful urge to move your legs): 6 people, 12.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 12.50%
Type 2 Diabetes: 5 people, 10.42%
Psychotic Disorder: 5 people, 10.42%
Post-Traumatic Stress Disorder: 5 people, 10.42%
Personality Disorder: 5 people, 10.42%
Peptic Ulcer Haemorrhage (peptic ulcer bleeding): 5 people, 10.42%

* Approximation only. Some reports may have incomplete information.

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